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Oxidative Stress Induced by Cadmium and Copper in Brassica rapa Leaves: Indicators of Stress, Oxidative Damage, and Antioxidant Mechanisms Universiteit Hasselt
Brassica rapa is frequently used as a vegetable for human consumption and can accumulate metals that are bioavailable in soils. We studied the oxidative stress induced by 25M cadmium (Cd) and 50M copper (Cu) on Brassica rapa leaves and evaluated the intracellular antioxidative plant response mechanisms and the accumulation of these metals. With this purpose, hydrogen peroxide (H2O2) concentration, lipid peroxidation, and enzymatic and ...
Association between heat stress and oxidative stress in poultry : mitochondrial dysfunction and dietary interventions with phytochemicals Universiteit Gent
Heat as a stressor of poultry has been studied extensively for many decades; it affects poultry production on a worldwide basis and has significant impact on well-being and production. More recently, the involvement of heat stress in inducing oxidative stress has received much interest. Oxidative stress is defined as the presence of reactive species in excess of the available antioxidant capacity of animal cells. Reactive species can modify ...
Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans Universiteit Gent
The superoxide radical (O-2(-)) has long been considered a major cause of aging. O-2(-) in cytosolic, extracellular, and mitochondrial pools is detoxified by dedicated superoxide dismutase (SOD) isoforms. We tested the impact of each SOD isoform in Caenorhabditis elegans by manipulating its five sod genes and saw no major effects on life span. sod genes are not required for daf-2 insulin/IGF-1 receptor mutant longevity. However, loss of the ...
Urinary polycyclic aromatic hydrocarbon metabolites are associated with biomarkers of chronic endocrine stress, oxidative stress, and inflammation in adolescents Vrije Universiteit Brussel KU Leuven Universiteit Hasselt Universiteit Gent Universiteit Antwerpen
Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants of public health concern. Multiple biological mechanisms have been hypothesized to contribute to PAHs-associated adverse health effects. Little is known about the impact of PAHs on endocrine stress and inflammation in adolescence. We examined 393 Flemish adolescents (14–15 years) cross-sectionally, measured urinary concentrations of hydroxylated naphthalene, fluorene, ...
Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells KU Leuven
Increase in cytosolic calcium concentration ([Ca2+](c)), release of endoplasmic reticulum (ER) calcium ([Ca2+](er)) and ER stress have been proposed to be involved in oxidative toxicity. Nevertheless, their relative involvements in the processes leading to cell death are not well defined. In this study, we investigated whether oxidative stress generated during ascorbate-driven menadione redox cycling (Asc/Men) could trigger these three events, ...
RNA interference links oxidative stress to the inhibition of heat stress adaptation Universiteit Gent
Increased oxidative stress is associated with various diseases and aging, while adaptation to heat stress is an important determinant of survival and contributes to longevity. However, the impact of oxidative stress on heat resistance remains largely unclear. Aim: In this study we investigated how oxidative stress impinges on heat stress responses. Results: We report that hydrogen-peroxide (H2O2) pretreatment inhibits both acquired ...
The peroxisomal import receptor PEX5 functions as a stress sensor, retaining catalase in the cytosol in times of oxidative stress KU Leuven
Accumulating evidence indicates that peroxisome functioning, catalase localization, and cellular oxidative balance are intimately interconnected. Nevertheless, it remains largely unclear why modest increases in the cellular redox state especially interfere with the subcellular localization of catalase, the most abundant peroxisomal antioxidant enzyme. This study aimed at gaining more insight into this phenomenon. Therefore, we first established ...
Effect of single or combined climatic and hygienic stress in four layer lines: 2. Endocrine and oxidative stress responses KU Leuven
Effects of long-term climatic stress (heat exposure), short-term hygienic stress [lipopolysaccharide (LPS)], or combined exposure to these stressors on endocrine and oxidative stress parameters of 4 layer lines (B1, WA, WB, and WF) were investigated. The lines were earlier characterized for natural humoral immune competence and survival rate. Eighty hens per line were randomly divided over 2 identical climate chambers and exposed to constant ...
Oxidative stress, leaf photosynthetic capacity and dry matter content in young mangrove plant Rhizophora mucronata Lam. under prolonged submergence and soil water stress Vrije Universiteit Brussel
Young plants of Rhizophora mucronata Lam. were tested for oxidative stress, photosynthetic capacity and dry matter accumulation under two abiotic stress conditions; prolonged submergence and soil water stress. The experiment of prolonged submergence was performed in field conditions with two treatment levels; 50% inundation (control) and 100% inundation levels. The experiment of soil water stress was conducted in a plant-house with four ...