Publicaties
The quiescin sulfhydryl oxidase (hQSOX1b) tunes the expression of resistin-like molecule alpha (RELM-α or mFIZZ1) in a wheat germ cell-free extract Vrije Universiteit Brussel
Methodology/Principal findings: We optimize an in vitro wheat ...
Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria Vrije Universiteit Brussel
Safety evaluation of the food enzyme catalase from porcine liver. Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Safety evaluation of the food enzyme catalase from the genetically modified Aspergillus niger strain DP-Azw58 Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Oxygen at Nanomolar Levels Reversibly Suppresses Process Rates and Gene Expression in Anammox and Denitrification in the Oxygen Minimum Zone off Northern Chile Vrije Universiteit Brussel
Would, early, versus late hydroxocobalamin dose intensification treatment, prevent cognitive decline, macular degeneration and ocular disease, in 5 patients with early-onset cblC deficiency? Vrije Universiteit Brussel
biochemical and clinical outcome. In mammals, Cobalamin is reduced, in a reaction mediated by MMACHC.
Pathogenic variants in MMACHC disrupt the synthesis pathway of methyl-cobalamin (MetCbl) and 5′-deoxyadenosyl-cobalamin (AdoCbl), cofactors for both methionine synthase (MS) and methyl-malonyl-CoA mutase
(MCM) enzymes. In ...
Isolated sulfite oxidase deficiency Vrije Universiteit Brussel KU Leuven
Isolated sulfite oxidase deficiency (ISOD) is a life-threatening, autosomal recessive disease characterized by severe neurological impairment. As no long-term effective treatment is available, distinction from other treatable diseases, such as molybdenum cofactor deficiency (MoCD) type A, should be made. We reviewed 47 patients (45 previously reported in the literature). Cases were reviewed for consanguinity, sex, age at onset, death, ...
Staphylococcus petrasii subsp. pragensis subsp. nov., occurring in human clinical material Vrije Universiteit Brussel Universiteit Gent
Seven coagulase-negative, oxidase-negative and novobiocin-susceptible staphylococci assigned tentatively as Staphylococcus petrasii were investigated in this study in order to elucidate their taxonomic position. All strains were initially shown to form a genetically homogeneous group separated from remaining species of the genus Staphylococcus by using a repetitive sequence-based PCR fingerprinting with the (GTG)5 primer. Phylogenetic ...
Simple colorimetric trypanothione reductase-based assay for high-throughput screening of drugs against Leishmania intracellular amastigotes Instituut voor Tropische Geneeskunde Universiteit Antwerpen
Critical to the search for new anti-leishmanial drugs is the availability of high-throughput screening (HTS) methods to test chemical compounds against the relevant stage for pathogenesis, the intracellular amastigotes. Recent progress in automated microscopy and genetic recombination has produced powerful tools for drug discovery. Nevertheless, a simple and efficient test for measuring drug activity against Leishmania clinical isolates is ...