Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
Understanding the molecular biology of membrane transport in a disease-related context covering Alzheimer’s disease and congenital disorders of glycosylation type II.
Research on the role of cell-surface interactions in specifying synaptic connectivity, understanding the molecular and cellular mechanisms that determine where and when synaptic connections form; how these connections change with experience, and how they are affected in disease, research on changes in connectivity, composition and function of synapses are thought to underlie memory processes and brain disorders such as autism and Alzheimer’s ...
Research on the role of cell-surface interactions in specifying synaptic connectivity, understanding the molecular and cellular mechanisms that determine where and when synaptic connections form; how these connections change with experience, and how they are affected in disease, research on changes in connectivity, composition and function of synapses are thought to underlie memory processes and brain disorders such as autism and Alzheimer’s ...
Research on the role of cell-surface interactions in specifying synaptic connectivity, understanding the molecular and cellular mechanisms that determine where and when synaptic connections form; how these connections change with experience, and how they are affected in disease, research on changes in connectivity, composition and function of synapses are thought to underlie memory processes and brain disorders such as autism and Alzheimer’s ...
Researching the mechanisms of acute and chronic axonal and neuronal degeneration and regeneration, aiming to contribute to the development of new therapeutic strategies for neurodegenerative disorders, studying motor neuron diseases (amyotrophic lateral sclerosis (ALS) and hereditary motor neuropathies), frontotemporal dementia (FTD) and stroke.
Understanding the mechanisms gearing protein folding and misfolding and their relation to human disease, investigating how protein aggregation affects the interactome by suppressing native interactions but also by introducing novel aggregation-specific interactions.
Understanding the mechanisms gearing protein folding and misfolding and their relation to human disease, investigating how protein aggregation affects the interactome by suppressing native interactions but also by introducing novel aggregation-specific interactions.