Determination of hydrogen, Carbon, Nitrogen, Oxygen and Sulphur isotope ratio's in a wide variety of matrix and samples (Delta D, Delta 13C, Delta 15N, Delta 13C, Delta 18O, and Delta 34S, clumped isotopes) using 2 Nu-Perspective instruments, 1 Nu-Horizon and 1 Delta V, connected to various peripherals
In de levenswetenschappen staat data centraal. Het steunt op het genereren, delen en het geïntegreerd analyseren van enorme hoeveelheden digitale data. ELIXIR is een Europese onderzoeksinfrastructuur die internationale diensten in levenswetenschappen samenbrengt tot een geïntegreerde infrastructuur die onderzoekers toelaat om data en expertise uit te wisselen, en toegang verschaft tot geavanceerde software en computationele resources, over disciplines en grenzen heen. De Belgische ELIXIR Node helpt onderzoekers om data te beheren en te analyseren, om Open Science toe te passen en onderzoek ...
The purpose of this proposal is to establish a state-of-the- art Liquid Chromatography Mass Spectrometry (LC-MS) Proteomics Platform at the VUB. This facility will be enabled by the acquisition of a state-of-the-art LC coupled to a trapped ion-mobility - time-of-flight (timsTOF) MS combined with specialist expertise, aimed to complement the world-leading genomic life-science research at the VUB to fully characterize complex biological systems with multi- omic data. The LC-MS platform will be optimized towards unprecedented resolving power and ultra-high detection sensitivity for deep ...
Nuclear Magnetic Resonance (NMR) is a core analytical technique for structure analysis in chemistry. It uses extremely strong magnetic fields in combination with radiofrequency pulses to manipulate the magnetic field of individual atomic nuclei into revealing clues on their surrounding molecular structure. Through various structure dependent parameters a multitude of windows are provided through which key information becomes available regarding individual molecular structure, size, shape and dynamics, all in a non-destructive fashion. As a result, NMR is indisputably THE core technique to ...
This application aims at maintaining and expanding the characterization of chemical compounds via mass spectrometry (MS) within the Research Group of Organic Chemistry (ORGC) at the VUB. The current MS equipment, for selected applications coupled to liquid chromatography (LC), serves to confirm the identity, purity and molecular fingerprint of compounds, some of which can only be validated via this technique (e.g. peptides, (labelled) proteins). While the available equipment runs continuously for routine analysis of various molecules, it is outdated and service on the machine cannot be ...
SiO2-based substrates (Borofloat, quartz, …) are essential for a wide range of optical, chemical, sensory, diagnostic and many other applications due to their generally chemically inert nature, optical transparency, dielectric properties, electrophilic nature and suitability to apply a wide range of coatings on. In general, it is desirable to pattern a substrate to create large surface areas for chemical interactions or to achieve well-defined flow configurations, so that e.g. novel or improved separation methods can be achieved. While very powerful (Bosch and cryogenic type) deep ...
Thermal activity monitoring (TAM) microcalorimetry is the single most sensitive calorimetric measurement technique, capable of measuring heat effects over time scales of days to months due to its high baseline stability. Because of this it is uniquely suited to study processes that slow down significantly at temperatures that are relevant for applications, and which therefore cannot be studied with more common calorimetric techniques such as DSC. The addition of perfusion accessories greatly extends the possibilities of the device by allowing a ...