Publicaties
Applicability of an effective conductivity approach in modeling thoracic impedance changes Vrije Universiteit Brussel
Isocratic and gradient impedance plot analysis and comparison of some recently introduced large size core-shell and fully porous particles KU Leuven
Morphology optimization and assessment of the performance limits of high-porosity nanostructured polymer monolithic capillary columns for proteomics analysis Vrije Universiteit Brussel
This study targets the synthesis of high external-porosity poly(styrene-co-divinylbenzene) monolithic support structures with macropore and globule sizes in the sub-micron range, aiming at the realization of high-speed and high-resolution gradient separations of intact proteins and peptides. The thermodynamic and kinetic aspects of the free-radical polymerization synthesis were adjusted by tuning the porogen to monomer ratio, the porogen ...
The future of UHPLC: Towards higher pressure and/or smaller particles? Vrije Universiteit Brussel
Reduction of Taylor-Aris dispersion by lateral mixing for chromatographic applications Vrije Universiteit Brussel
Chromatographic columns are suffering from Taylor-Aris dispersion, especially for slowly diffusing molecules such as proteins. Since downscaling the channel size to reduce Taylor-Aris dispersion meets fundamental pressure limitations, new strategies are needed to further improve chromatography beyond its current limits. In this work we demonstrate a method to reduce Taylor-Aris dispersion by lateral mixing in a newly designed silicon ...
Phase-dependent dielectric properties and proton conduction of neopentyl glycol KU Leuven
Kinetic performance factor - A measurable metric of separation-time-pressure tradeoff in liquid and gas chromatography Vrije Universiteit Brussel
A measurable dimensionless metric of tradeoff between separation, time and pressure in chromatography – the kinetic performance factor (e c) is introduced. Measurable the same way for all LC and GC columns (open-tubular, packed, monolithic, pillar-array, etc.) regardless of retention mechanism, e c supersedes metrics of a column structural quality such as dimensionless plate height (h), Bristow-Knox separation impedance (SI), Golay specific ...