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Influence of surgical excision on the survival of patients with stage 4 high-risk neuroblastoma : a report from the HR-NBL1/SIOPEN study Universiteit Gent
Peak oxygen uptake, ventilatory efficiency and QRS-duration predict event free survival in patients late after surgical repair of tetralogy of Fallot KU Leuven
Patients with repaired tetralogy of Fallot (ToF) have an increased long-term risk of cardiovascular morbidity and mortality. Risk stratification in this population is difficult. Initial evidence suggests that cardiopulmonary exercise testing (CPET) may be helpful to risk-stratify patients with repaired ToF.
Leukemia-free survival as a surrogate end point for overall survival in the evaluation of maintenance therapy for patients with acute myeloid leukemia in complete remission Universiteit Hasselt
Background In trials designed to evaluate new therapies for hematologic malignancies, end points such as leukemia-free survival are often used as surrogates for overall survival in acute leukemia. We aimed to assess whether leukemia-free survival is an acceptable statistical surrogate for overall survival when applied to remission maintenance therapy for acute myeloid leukemia. Design and Methods Data were analyzed from a randomized Phase III ...
The long-term survival of Escherichia coli O157:H7 and Salmonella on lettuce seeds and their subsequent survival and growth on germinating sprouts Instituut voor Landbouw-, Visserij- en Voedingsonderzoek
Introduction
In recent years, numerous outbreaks with enteric pathogens have been associated with contaminated sprouts (2,3). Moreover, evidence suggests that the recent outbreaks in Germany and France with Escherichia coli O104:H4 could be attributed to contaminated seeds, namely fenugreek seeds (1). These seeds had possibly been contaminated for up to two years. But until now, bacteriological evidence for this hypothesis is lacking. ...
Progression free survival rate at 9 and 18 weeks predict overall survival in patients with malignant pleural mesothelioma: an individual patient pooled analysis of 10 European Organisation for Research and Treatment of Cancer Lung Cancer Group studies and Universiteit Gent Universiteit Antwerpen
Progression-free survival as surrogate end point for overall survival in clinical trials of HER2-targeted agents in HER2-positive metastatic breast cancer Universiteit Hasselt
Background: The gold standard end point in randomized clinical trials in metastatic breast cancer (MBC) is overall survival (OS). Although therapeutics have been approved based on progression-free survival (PFS), its use as a primary end point is controversial. We aimed to assess to what extent PFS may be used as a surrogate for OS in randomized trials of anti-HER2 agents in HER2+ MBC. Eligible trials accrued HER2+ MBC patients in 1992-2008. A ...
Adjusting for timeU+2010varying confounders in survival analysis using structural nested cumulative survival time models Universiteit Gent
Long-term survival of Escherichia coli O157:H7 and Salmonella enterica on butterhead lettuce seeds, and their subsequent survival and growth on the seedlings Instituut voor Landbouw-, Visserij- en Voedingsonderzoek Universiteit Gent
The long-term survival of enteric pathogens on butterhead lettuce seeds, and their subsequent survival and growth on seedlings were investigated. Lettuce seeds were inoculated at a high level with two Salmonella enterica and two Escherichia coli O157:H7 strains each (±8 log10 CFU/g seed) and the survival of the pathogens was monitored over two years using standard plating techniques on selective medium. The Salmonella strains (serovars ...