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The accuracy of pleural biopsy via fiber optic bronchoscope Universiteit Gent
Revolutionizing sample preparation: a novel autonomous microfluidic platform for serial dilution KU Leuven
Dilution is a standard fluid operation widely employed in the sample preparation process of many bio(chemical) assays. It serves multiple essential functions such as sample mixing with certain reagents at specific dilution ratios, reducing sample matrix effects, bringing target analytes within the linear assay detection range, among many others. Traditionally, sample processing is performed in laboratory settings through manual or automated ...
Human immunodeficiency virus care and management in incarcerated populations in Sub-Saharan Africa between 2010 and 2022: a narrative review Instituut voor Tropische Geneeskunde
Background: Different countries in sub-Saharan Africa (SSA) have established guidelines to reduce HIV transmission and improve its management in prisons. This narrative review aimed to examine established literature on HIV care and management among incarcerated persons in SSA to identify successful interventions that could inform improved guidelines, policies, and practices related to the clinical care of this population.
Methods: ...
Risk factors and circulation pattern of respiratory syncytial virus in children under 2 years in Maputo, Mozambique Instituut voor Tropische Geneeskunde
Background
Evidence on risk factors for respiratory syncytial virus (RSV) in low-resource settings is limited. In Mozambican children <2 y of age with severe acute respiratory infection (SARI), we explored risk factors for RSV, described its seasonal variation and assessed associations between RSV and a life-threatening condition.
Methods
We retrospectively included participants presenting in 2017–2018 in two hospitals in ...
Evidence on risk factors for respiratory syncytial virus (RSV) in low-resource settings is limited. In Mozambican children <2 y of age with severe acute respiratory infection (SARI), we explored risk factors for RSV, described its seasonal variation and assessed associations between RSV and a life-threatening condition.
Methods
We retrospectively included participants presenting in 2017–2018 in two hospitals in ...
Uptake and challenges with daily oral pre-exposure prophylaxis among men who have sex with men and transgender women, suburban Yangon, Myanmar Instituut voor Tropische Geneeskunde
Background
Pre-exposure prophylaxis (PrEP) is effective for human immunodeficiency virus (HIV) prevention in risk groups. We assessed PrEP uptake and 12-month retention among men who have sex with men (MSM) and transgender women (TGW) in Myanmar during the coronavirus disease 2019 pandemic and a political crisis.
Methods
Using prospectively collected data, we assessed the proportion of persons eligible, initiated and ...
Pre-exposure prophylaxis (PrEP) is effective for human immunodeficiency virus (HIV) prevention in risk groups. We assessed PrEP uptake and 12-month retention among men who have sex with men (MSM) and transgender women (TGW) in Myanmar during the coronavirus disease 2019 pandemic and a political crisis.
Methods
Using prospectively collected data, we assessed the proportion of persons eligible, initiated and ...
Effect of dolutegravir-based versus efavirenz-based antiretroviral therapy on excessive weight gain in adult treatment-naïve HIV patients at Matsanjeni health center, Eswatini: a retrospective cohort study Instituut voor Tropische Geneeskunde
Background
There is limited data on dolutegravir (DTG)-associated weight gain from settings with a dual burden of HIV and overnutrition.
Methods
In Eswatini (at Matsanjeni), among 156 and 160 adult patients on DTG-based and EFV-based antiretroviral therapy (ART), respectively, we studied excessive weight gain (BMI at 24 months ART greater than baseline and ≥25 kg/m2).
Results
The median BMI increase in ...
There is limited data on dolutegravir (DTG)-associated weight gain from settings with a dual burden of HIV and overnutrition.
Methods
In Eswatini (at Matsanjeni), among 156 and 160 adult patients on DTG-based and EFV-based antiretroviral therapy (ART), respectively, we studied excessive weight gain (BMI at 24 months ART greater than baseline and ≥25 kg/m2).
Results
The median BMI increase in ...
Development of antepartum risk prediction model for postpartum hemorrhage in Lagos, Nigeria: A prospective cohort study (Predict-PPH study) Instituut voor Tropische Geneeskunde
OBJECTIVES: There is currently a limited ability to accurately identify women at risk of postpartum hemorrhage (PPH). We conducted the "Predict-PPH" study to develop and evaluate an antepartum prediction model and its derived risk-scoring system.
METHODS: This was a prospective cohort study of healthy pregnant women who registered and gave birth in five hospitals in Lagos, Nigeria, from January to June 2023. Maternal antepartum ...
Realist evaluation of a community-based antiretroviral therapy (CBART) programme for key populations in Benue State in Nigeria Instituut voor Tropische Geneeskunde Universiteit Antwerpen
Background
World Health Organization recommended community-based ART (CBART) approaches to improve access to antiretroviral treatment (ART) and treatment outcomes among key populations living with (KPLHIV). Key populations (KP) are female sex workers, men who have sex with men, persons who inject drugs, and transgender people. How CBART for KP (KP-CBART) worked and why, for whom and in what circumstances it worked within KP communities or ...
World Health Organization recommended community-based ART (CBART) approaches to improve access to antiretroviral treatment (ART) and treatment outcomes among key populations living with (KPLHIV). Key populations (KP) are female sex workers, men who have sex with men, persons who inject drugs, and transgender people. How CBART for KP (KP-CBART) worked and why, for whom and in what circumstances it worked within KP communities or ...
Understanding male circumcision: insights from a peri-urban community in Maputo City, Mozambique Instituut voor Tropische Geneeskunde
Background
Circumcision is a protective measure against sexually transmitted infections (STIs), reducing the risk of HIV infection. This study reported coverage of male circumcision and assessed the factors associated with male uncircumcision in a peri-urban area in Maputo City, Mozambique.
Methods
This cross-sectional study of the Health Demographic Surveillance System in the Polana Caniço neighborhood investigated the ...
Circumcision is a protective measure against sexually transmitted infections (STIs), reducing the risk of HIV infection. This study reported coverage of male circumcision and assessed the factors associated with male uncircumcision in a peri-urban area in Maputo City, Mozambique.
Methods
This cross-sectional study of the Health Demographic Surveillance System in the Polana Caniço neighborhood investigated the ...