Publicaties
Increased ventilation heterogeneity in asthma can be attributed to proximal bronchioles Vrije Universiteit Brussel
The effect of conductive ventilation heterogeneity on diffusing capacity measurement Vrije Universiteit Brussel
It has long been assumed that the ventilation heterogeneity associated with lung disease could, in itself, affect the measurement of carbon monoxide transfer factor. The aim of this study was to investigate the potential estimation errors of carbon monoxide diffusing capacity (D-LCO) measurement that are specifically due to conductive ventilation heterogeneity, i.e., due to a combination of ventilation heterogeneity and flow ...
Ventilation heterogeneity in the acinar and conductive zones of the normal ageing lung. Vrije Universiteit Brussel
Relationships between the lung clearance index and conductive and acinar ventilation heterogeneity. Vrije Universiteit Brussel
Acinar and conductive ventilation heterogeneity in severe CF lung disease: back to the model. Vrije Universiteit Brussel
Ventilation heterogeneity in smokers Vrije Universiteit Brussel
Smoking-induced ventilation heterogeneity measured at the mouth via established washout indices (lung clearance index LCI and alveolar mixing efficiency AME) potentially results from unequal expansion, which can be quantified by CT, and structural changes down to the lung periphery, characterized by CT parametric response mapping indices (PRMfSAD,PRMEmph). By combining CT imaging and N2 washout tests in smokers, we specifically examined the ...
Noninvasive measures of lung structure and ventilation heterogeneity Vrije Universiteit Brussel
Airway function at different lung depths can be determined non-invasively via ventilation distribution tests, by measuring either gases or aerosols at the mouth. After having a subject inhale a well-characterized amount of gas or aerosol in a well-controlled breathing maneuver, the expired gas or aerosol trace can be analyzed to represent critical structural and functional features of the lung. One such feature is the asymmetry of the lung, ...