Axonal transport defects in C9orf72 ALS/FTD: the role of dipeptide repeat proteins KU Leuven
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are adult-onset neurodegenerative diseases that are characterized by the degeneration of motor neurons in the spinal cord, brainstem, and motor cortex, or neurons in the frontal and anterior temporal cortex, respectively. In recent years, it has become evident that ALS and FTD belong to the same disease spectrum as these two diseases share several clinical, neuropathological, ...