Monovinyl Sulfone β-Cyclodextrin. A Flexible Drug Carrier System Vrije Universiteit Brussel
Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad?hoc synthesis of each cyclodextrin-targeting agent conjugate. We hypothesized that: 1)?a modular design that decouples the carrier function from the targeting function leads to a flexible system, 2)?combining the reactivity of the ...