Publicaties
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A low cost photonic biosensor built on a polymer platform Universiteit Gent
Planar integrated optical biosensors are becoming more and more important as they facilitate label-free and real time monitoring biosensing with high sensitivity. In this paper, the systematic research on one kind of optical biosensor, based on a resonant principle in a polymer ring resonator, will be presented. Reduced footprint and high sensitivity are advantages of this kind of biosensor. Rather than expensive CMOS fabrication, the device ...
Using a cell-based gas biosensor for investigation of adverse effects of acetone vapors in vitro Universiteit Hasselt
In this study, a cell-based gas biosensor is presented used for the detection and investigation of gaseous organic compounds in air. The response of living human nasal cells (RPMI 2650) and human lung cells (A549) towards the direct exposure of gaseous substances for 10 min is monitored with a multiparametric sensor system. Changes in the cellular impedance, oxygen consumption rate and acidification rate can be recorded after the exposure and ...
SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications Universiteit Gent
The materialization of an impedimetric biosensor to detect papillomavirus DNA based on indium oxide nanowires Universiteit Hasselt
In this study, the impedimetric biosensor of human papillomavirus DNA (HPV DNA) in label-free approach based on indium oxide nanowires (In2O3 NWs) was fabricated. The fabrication of In2O3 NWs was successfully conducted using the thermal evaporation method and catalyst-free approach. The grown NWs had a diameter of about 70-90 nm and a length of several microns. The fabricated electrode was able to show high selectivity by changing the relative ...
Enhanced Biosensor Platforms for Detecting the Atherosclerotic Biomarker VCAM1 Based on Bioconjugation with Uniformly Oriented VCAM1-Targeting Nanobodies Universiteit Hasselt KU Leuven
Surface bioconjugation of biomolecules has gained enormous attention for developing advanced biomaterials including biosensors. While conventional immobilization (by physisorption or covalent couplings using the functional groups of the endogenous amino acids) usually results in surfaces with low activity, reproducibility and reusability, the application of methods that allow for a covalent and uniformly oriented coupling can circumvent these ...
Customized impedance spectroscopy device as possible sensor platform for biosensor applications Universiteit Hasselt KU Leuven
A new impedeance spectroscopy unit is developed fully customized to become a vital part of label free biosensor arrays with possible applications in DNA and protein sensing Test measurements are conducted to expolre the accuracy and specificity of the system, both under electronic lab conditions as well as under wet cell conditions with synthetic-diamond based sensor electrodes. The impedance of seven resistors was monitored for 17h and a ...