Projecten
Chronische ontsteking en cardiovasculair risico KU Leuven
Cardiovascular disease is the leading cause of death and illness globally. Preventive therapies can avoid or delay the occurrence of cardiovascular events, provided that one can identify individuals at risk and intervene before problems manifest. Recent scientific developments have established that inflammation has a prominent role in the development of cardiovascular diseases; but routine screening of inflammatory markers to assess ...
Geïndividualiseerde zorg voor ouderen met complexe chronische aandoeningen thuis en in verpleeghuizen KU Leuven
BACKGROUND
Optimal care for older patients with complex chronic conditions (CCC) is challenging. Not only do older patients with CCC present with multiple conditions and functional impairments, these often interact with each other, as well as with their treatments.
Patients with CCC are concentrated in home care and nursing home settings. Professionals working in these settings often lack appropriate decision support that mirrors ...
Patiënten en verzorgers verbinden met behulp van draagbare sensortechnologie KU Leuven
Safest, reliable, individualised care of patients at-risk of deterioration needs patients themselves to play an active role in their care whenever possible: late detection or escalation of deterioration causes avoidable harms, and deaths. In this project we will challenge industry to develop robust monitoring and communications systems that connect patients, carers and health professionals, provide early warning of acute deterioration in and ...
HeMiBio Vrije Universiteit Brussel
In the project we made the following advances beyond the state of the art:
1. CELLS: We characterized for the first ...
Op BIOmarker gebaseerde diagnostische TOOLkit om farmacologische benaderingen bij congestief hartfalen te personaliseren KU Leuven
Heart failure (HF) is a chronic clinical condition involving up to 6.5 million people in Europe, the most frequent cause of hospitalization in adults with a 5-year mortality rate up to 70%. Several drugs positively modify the course of disease in the patients with HF with reduced ejection fraction (HFrEF), with a high level of evidence. Besides, the use of diuretics, the basic cornerstone of symptoms relief in HFrEF by targeting congestion, ...
B-specific: B-celgerelateerde gen- en eiwitmarkers met prognostische en therapeutische waarde voor hart-en vaatziekten KU Leuven
Atherosclerosis is the major underlying condition of cardiovascular disease (CVD) and one the leading causes of mortality. Rupture or erosion of atherosclerotic lesions can lead to acute cardiovascular events, such as myocardial infarction and stroke, making biomarkers to diagnose patients at risk for these events and develop tailored preventive interventions, an urgent need. Although atherosclerosis is a chronic inflammatory disease, ...
Nieuwe diagnostische en therapeutische benadering van inflammatoire darmaandoeningen op basis van functionele karakterisering van patiënten: de CrUCCial-index KU Leuven
The clinical phenotype and the outcome of Crohn's disease (CD) and ulcerative colitis (UC), the opposite ends of chronic inflammatory bowel diseases (IBD), are heterogeneous and represent the result of a complex interplay of the gut microbiome with the immune system in genetically predisposed individuals. Disease management is much less heterogeneous as all patients are treated using non-specific anti-inflammatory agents, and only 30-50% ...