The Central role of Macrophages in Trypanosomiasis-Associated Anemia: Rationale for Therapeutical Approaches. Vrije Universiteit Brussel
Bovine African trypanosomiasis causes severe economical problems on the African continent and one of the most prominent immunopathological parameters associated with this parasitic infection is anemia. In this report we review the current knowledge of the mechanisms underlying trypanosomiasis-associated anemia. In first instance, the central role of macrophages and particularly their activation state in determining the outcome of the disease ...