Publicaties
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A systematic review and meta-analysis on the radiation dose of computed tomography in hybrid nuclear medicine imaging Universiteit Gent
Thoracoscopic hybrid ablation in a patient with drug refractory arrhythmogenic right ventricular cardiomyopathy combined with non-invasive electrocardiographic imaging Vrije Universiteit Brussel
We performed an electrocardiographic imaging (ECGi) study during the hybrid-approach ablation of a 50-year-old man affected by arrhythmogenic right ventricular cardiomyopathy (ARVC), with documented ventricular tachycardia (VT) and intolerance to anti-arrhythmic drugs. In this patient, the VT induction protocol during the hybrid procedure induced monomorphic VT having the same characteristics of the clinical VT. We used the ECGi to compare the ...
Hybrid imaging labels : providing the link between mass spectrometry-based molecular pathology and theranostics Universiteit Gent
Clinical Perspectives of Hybrid Proton-Fluorine Magnetic Resonance Imaging and Spectroscopy Vrije Universiteit Brussel
bstract: The number of applications of fluorine 19 (19F) magnetic resonance (MR) imaging and spectroscopy in biomedical and clinical research is steadily growing. The 100% natural abundance of fluorine and its relatively high sensitivity for MR (83% to that of protons) make it an interesting nucleus for a wide range of MR applications. Fluorinated contrast media have a number of advantages over the conventionally used gadolinium-based or ...
Development, validation and application of a hybrid simulation technique for cone beam CT in head and neck imaging KU Leuven
X-ray Computed Tomography (CT) is one of the most important means in current medical imaging. The theory was originally proposed by Godfrey N Hounsfield in 1967. Today, the CT scanners have evolved enormously, in both system design and imaging performance. Cone beam computed tomography (CBCT) is a relatively new CT technique with applications in diagnostic radiology, image-guided surgery and image-guided radiotherapy. The most prominent feature ...
Multimodal Imaging Mass Spectrometry to Identify Markers of Pulmonary Arterial Hypertension in Human Lung Tissue Using MALDI-ToF, ToF-SIMS, and Hybrid SIMS KU Leuven
Pulmonary arterial hypertension (PAH) is a rare and deadly disease affecting roughly 15-60 people per million in Europe with a poorly understood pathology. There are currently no diagnostic tools for early detection nor does a curative treatment exist. The lipid composition of arteries in lung tissue samples from human PAH and control patients were investigated using matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry ...
Development and validation of a hybrid simulation technique for cone beam CT: application to an oral imaging system KU Leuven
This paper proposes a hybrid technique to simulate the complete chain of an oral cone beam computed tomography (CBCT) system for the study of both radiation dose and image quality. The model was developed around a 3D Accuitomo 170 unit (J Morita, Japan) with a tube potential range of 60-90 kV. The Monte Carlo technique was adopted to simulate the x-ray generation, filtration and collimation. Exact dimensions of the bow-tie filter were estimated ...
Multiplex core of the human brain using structural, functional and metabolic connectivity derived from hybrid PET-MR imaging. KU Leuven
With the increasing success of mapping brain networks and availability of multiple MR- and PET-based connectivity measures, the need for novel methodologies to unravel the structure and function of the brain at multiple spatial and temporal scales is emerging. Therefore, in this work, we used hybrid PET-MR data of healthy volunteers (n = 67) to identify multiplex core nodes in the human brain. First, monoplex networks of structural, functional ...