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Sequencen van individuele cellen voor het bestuderen van chromosoom instabiliteit in embryos en de origine van structurele genetische variatie KU Leuven
Although a cell produces an assortment of products that protect, inspect and if necessary heal its valuable genetic code, DNA-mutations can accumulate during a cell’s life cycle. This is exemplified by the acquisition of somatic genetic lesions that cause cancer, but also by the birth of disabled children due to a genomic aberration acquired during gametogenesis or early embryogenesis. In fact, most likely we all are genetic mosaics early on or ...
De Tibetaanse sneeuwleeuw: brullen in de mist Universiteit Gent
Nieuwe inzichten in de rol van myeloïde cellen tijdens darmontsteking KU Leuven
Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract leading to debilitating symptoms such as bloody diarrhea, fatigue and weight loss. To date, no efficient therapies are available for IBD, resulting into an invaluable impact on the emotional, financial and social state of the patients and their families. Although over the last few decades most of the studies on IBD have looked into abnormal ...
Ondertussen in het hertogdom Brabant: huilen om de hertog Universiteit Antwerpen
Mesenchymale stromale cellen in de hematologie : klinische toepassingen KU Leuven
Mesenchymal stromal cells (MSCs) are multipotent stromal cells able to differentiate into adipocytes, chondrocytes and osteocytes. The role of MSC therapy in regenerative medicine is a topic of many studies. MSCs also display exceptional immunological capacities. They suppress activated T lymphocytes and are able to suppress acute graft-versus-host disease (GvHD) after a hematopoietic stem cell transplantation. HLA matching is not required for ...