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Anthonis de Roovere, Gerard Leeu en geïllustreerde rederijkersgedichten in de late 15de eeuw Universiteit Antwerpen
Gene Signatures Detect Damaged Liver Sinusoidal Endothelial Cells in Chronic Liver Diseases Vrije Universiteit Brussel
Liver sinusoidal endothelial cells have a gatekeeper function in liver homeostasis by permitting substrates from the bloodstream into the space of Disse and regulating hepatic stellate cell activation status. Maintenance of LSEC's highly specialized phenotype is crucial for liver homeostasis. During liver fibrosis and cirrhosis, LSEC phenotype and functions are lost by processes known as capillarization and LSEC dysfunction. LSEC ...
The interplay between endogenous inflammatory mediators and microbial components in innate immunity KU Leuven
HCV is a hepatotropic virus with a global prevalence rate of approximately 70 million individuals worldwide. Following HCV infection, the majority of individuals develop a chronic infection that is characterized by the occurrence of hepatic fibrosis and HCC. While great strides have been made understanding and treating HCV infection, there remains much to be revealed. In this thesis, we were interested in determining the role of HCV proteins ...
Carfilzomib weekly plus melphalan and prednisone in newly diagnosed transplant-ineligible multiple myeloma (IFM 2012-03) : a phase I trial Universiteit Gent
Purpose: Carfilzomib is a novel generation proteasome inhibitor. The Carmysap trial demonstrated that twice-weekly KMP (carfilzomib, melphalan, prednisone) might challenge the MPV (melphalan, prednisone, bortezomib) standard. We sought to studyKMPweekly, allowing to increase carfilzomib's dose with maintained efficacy and improved safety profile. Patients and Methods: IFM2012-03, a phase I multicenter study of KMP weekly in elderly patients with ...
Carfilzomib weekly plus melphalan and prednisone in newly diagnosed elderly multiple myeloma (IFM 2012-03) Universiteit Gent
IFM2012-03 Universiteit Gent
Carfilzomib weekly plus melphalan and prednisone in newly diagnosed elderly multiple myeloma (IFM 2012-03) Universiteit Gent
Burden of respiratory syncytial virus infection in community-dwelling older adults in Europe (RESCEU): an international prospective cohort study KU Leuven Universiteit Antwerpen
BACKGROUND: Respiratory syncytial virus (RSV) infection in older adults is recognised as an important health issue. We aimed to assess the community burden of RSV in Europe in older adults aged ≥60 years. METHODS: This international, prospective, observational cohort study is part of work by the REspiratory Syncytial virus Consortium in EUrope (RESCEU). Participants were recruited through general practitioners' (GPs) offices before two ...
Contact with young children increases the risk of respiratory infection in older adults in Europe Universiteit Antwerpen
Background Knowledge about how older adults get a respiratory infection is crucial for planning preventive strategies. We aimed to determine how contact with young children living outside of the household affects the risk of acute respiratory tract infections (ARTI) in community-dwelling older adults. Methods This study is part of the European RESCEU older adult study. Weekly surveillance was performed to detect ARTI throughout 2 winter seasons ...