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Factors associated with poor sleep in children with drug-resistant epilepsy KU Leuven

Renee Proost, Lieven Lagae, Wim Van Paesschen, Katrien Jansen
OBJECTIVE: We aimed to investigate sleep in children with drug-resistant epilepsy (DRE), including developmental and epileptic encephalopathies (DEEs). Next, we examined differences in sleep macrostructure and microstructure and questionnaire outcomes between children with well-controlled epilepsy (WCE) and children with DRE. Furthermore, we wanted to identify factors associated with poor sleep outcome in these children, as some factors might be ...

Role of Nasal Surgery in Adult Obstructive Sleep Apnea: A Systematic Review KU Leuven

Diego Conti
Objective  To perform a systematic review to determine if isolated nasal surgery has any impact on subjective or objective parameters in adult obstructive sleep apnea (OSA) patients. Materials and Methods  From December 2022 to March 2023, we conducted a search on the PubMed, Cochrane, Scopus, and Web of Science databases. Two independent investigators performed a study selection according to the established criteria, as well as data collection, ...

International Variability of Barriers to Adherence to Immunosuppressive Medication in Adult Heart Transplant Recipients. A Secondary Data Analysis of the BRIGHT Study KU Leuven

Sabina De Geest
Non-adherence to immunosuppressive medication among transplant patients is associated with poor clinical outcomes and higher economic costs. Barriers to immunosuppressives are a proximal determinant of non-adherence. So far, international variability of barriers to adherence in transplantation has not been studied. As part of the cross-sectional multi-country and multi-center BRIGHT study, barriers to adherence were measured in 1,382 adult heart ...

Experimental Study Of The Wave Field Around A Monopile Due To Moderate Steepness Irregular Incident Waves KU Leuven

Pieter Rauwoens
Most offshore wind turbine foundations are of monopile type and need regular marine operations to be conducted nearby during the lifetime of the turbine. Proper wave estimation around the monopile is needed to assure the safety of the operations. The trend of increasing monopile's diameter also adds the need to investigate the wave field around the increased monopile diameter for the marine operation analysis. Experimental campaigns of wave ...

ERS International Congress 2023: highlights from the Sleep Disordered Breathing Assembly KU Leuven

Dries Testelmans
The topic of sleep-related breathing disorders is always evolving, and during the European Respiratory Society (ERS) International Congress 2023 in Milan, Italy, the latest research and clinical topics in respiratory medicine were presented. The most interesting issues included new diagnostic tools, such as cardiovascular parameters and artificial intelligence, pathophysiological traits of sleep disordered breathing from routine polysomnography ...

Prolonged theoretical classes impact students' perceptions Vrije Universiteit Brussel

Petra Kotnik, Bart Roelands, Špela Bogataj

Mental fatigue (MF) arises during prolonged demanding cognitive activity and results in acute feelings of tiredness and a decreased physical and/or cognitive performance capacity. An often-overlooked population that is significantly at risk for the development of MF are university students. The current study investigated the impact of prolonged in-person theoretical classes on the perceptions of MF, boredom, and sleepiness among 27 Slovenian ...

Long-term efficacy and safety of pitolisant for residual sleepiness due to OSA Universiteit Antwerpen

Jean-Louis Pépin, Valérie Attali, Christian Caussé, Johan Verbraecken, Jan Hedner, Isabelle Lecomte, Renaud Tamisier, Patrick Lévy, Philippe Lehert, Yves Dauvilliers, et al.
Background In people with OSA, excessive daytime sleepiness is a prominent symptom and can persist despite adherence to CPAP, the first-line therapy for OSA. Pitolisant was effective in reducing daytime sleepiness in two 12-week randomized controlled trials (RCTs), one in patients adherent to CPAP (BF2.649 in Patients With OSA and Treated by CPAP But Still Complaining of EDS [HAROSA 1]) and the other in patients refusing or not tolerating CPAP ...

The DS-14 questionnaire Vrije Universiteit Brussel Universiteit Antwerpen

Sonia De Weerdt, Christiaan Schotte, Kurt Barbé, Sylvia Verbanck, Johan Verbraecken

Abstract: Little is known about type D personality in patients with obstructive sleep apnea (OSA). The DS-14 questionnaire is the standard tool to assess this personality type, but it has not been properly validated in patients with OSA, nor has it been correlated with clinical features in these patients. Purpose: To determine the internal consistency and test-retest reliability of the DS-14 questionnaire, as well as the prevalence of type D ...

Sleep impairment and altered pattern of circadian biomarkers during a long-term Antarctic summer camp Vrije Universiteit Brussel

Michele Macedo Moraes, Alice Lamounier Marques, Leandro Borges, Elaine Hatanaka, Debora Heller, Cristian Núñez-Espinosa, Dawit Albieiro Pinheiro Gonçalves, Danusa Soares Dias, Samuel Penna Wanner, Thiago Teixeira Mendes, et al.

Antarctic expeditions include isolation and exposure to cold and extreme photoperiods (with continuous natural light during summer) that may influence psychophysiological responses modulated by luminosity and sleep. We assessed changes in night sleep patterns by actigraphy, salivary biomarkers, and perceptual variables in seven participants in the following time points along a 50-day camping expedition in Antarctica (Nelson Island): Pre-Field ...

Sleep parameters and problems in adolescents with and without ADHD: A systematic review and meta‐analysis KU Leuven

Finja Marten, Lena Keuppens, Dieter Baeyens, Marina Danckaerts, Saskia Van der Oord
BACKGROUND: Adolescence is characterized by an increase in the rate of sleep problems, which might be even more pronounced in adolescents with ADHD. This systematic review with meta-analysis aimed to compare sleep in adolescents with and without ADHD, including sleep parameters, both subjectively and objectively measured, sleep problems and sleep hygiene. METHODS: Medline, CINAHL, PsycINFO, EMBASE, ERIC, Web of Science, and PubMed databases were ...