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Réseau d'Etude IMT/CE sur la Trypanotolérance Instituut voor Tropische Geneeskunde
IMT/EC Trypanotolerance Study Network Instituut voor Tropische Geneeskunde
Both type-1 and type-II responses contribute to murine trypanotolerance. Vrije Universiteit Brussel
The host immune system has been documented to influence the course and outcome of infection with the phospholipase-C-deficient (PLC-/-) Trypanosoma brucei brucei. We addressed the resistant mechanisms during trypanosomosis by comparing the immune response to variant-specific surface glycoprotein (VSG) in relatively susceptible C3H mice and trypanotolerant (C57Bl/xBALB/c)-F1 (B6B-F1) mice infected with PLC-/- parasites. During the early stage of ...