Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions Instituut voor Tropische Geneeskunde Universiteit Hasselt
Immunologically, active visceral leishmaniasis (VL) is characterized by profound immunosuppression, severe systemic inflammatory responses, and an impaired capacity to control parasite replication. Neutrophils are highly versatile cells, which play a crucial role in the induction as well as the resolution of inflammation, the control of pathogen replication, and the regulation of immune responses. Neutrophil functions have been investigated ...