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Organisation
Research Group Molecular Neurobiology (VIB-KU Leuven)
Division
Main organisation:Department of Neurosciences
Lifecycle:1 Jan 2017 → Today
Organisation profile:
Major research questions focus on cell type vulnerability and single-cell heterogeneity, protein aggregation and proteopathic stress, synaptic function, as well as microglial activation and neuroimmunology.
Keywords:Neurobiology
Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing, Laboratory medicine
Sub-organisation(s)
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- Laboratory of Proteolytic Mechanisms in Neurodegeneration (VIB-KU Leuven)
- Laboratory of Neuronal Communication (VIB-KU Leuven)
- Laboratory of Neuronal Differentiation (VIB-KU Leuven Center for Brain & Disease Research)
- Laboratory of Emotional Circuit Development (VIB-KU Leuven)
- Laboratory of Interneuron Developmental Dynamics (VIB-KU Leuven)
- Laboratory of Sleep and Synaptic Plasticity (VIB-KU Leuven)
- Laboratory of Membrane Trafficking (VIB-KU Leuven)
- Laboratory of Neurophysiology in Neurodegenerative Disorders (VIB- KU Leuven)
- Laboratory of Synapse Biology (VIB-KU Leuven)
- Neuronal Wiring Lab (VIB-KU Leuven)
Current researchers
1 - 10 of 12 results
- Natalia Gunko (Member)
- Véronique Hendrickx (Member)
- Henne Holstege (Member)
- Esther Klingler (Member)
- Sebastian Munck (Member)
- Nicolas Peredo (Member)
- Angéle Pouwels (Member)
Projects
1 - 10 of 28
- Impact of Genetic Risk factors and Ageing on Neuronal organellar and lipid homeostasis in Parkinson and Alzheimer’s disease – GRAN’PAFrom1 Oct 2025 → TodayFunding: BOF - projects
- Myelination and plasticity: oligodendrocyte development across brain regions with different plasticity periods.From20 Aug 2025 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Acquisition of a cryo-holder for an existing JEOL F200 electron microscope to enable structural biology applications in the context of human diseaseFrom1 Jan 2025 → TodayFunding: BOF - scientific equipment program
- Acquisition of a cryo-holder for an existing JEOL F200 electron microscope to enable structural biology applications in the context of human diseaseFrom1 Jan 2025 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unraveling the protection of a centenarian microglia to Alzheimer's disease pathologyFrom1 Oct 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Role of amygdala in the etiology of ASD: identify maternal immune activation sensitive genes and cell types during amygdala development.From1 Oct 2024 → TodayFunding: Foundations, funds and other with scientific goal
- Emergence of amygdala neuronal diversityFrom18 Sep 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- Replace a broken freeze substitution low temperature embedding system for light and electron microscopy (Leica EM AFS2)From1 Jan 2023 → 31 Dec 2024Funding: BOF - scientific equipment program
- Single-objective light sheet instrument for fast and highthroughput imaging of 3D tissueFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
Publications
1 - 10 of 199
- Inhomogeneity Based Characterization of Distribution Patterns on the Plasma Membrane(2016)Published in: PLoS Computational BiologyISSN: 1553-734XIssue: 9Volume: 12
- Alterations in phosphatidylethanolamine levels affect the generation of Aβ(2012)Published in: Aging CellISSN: 1474-9718Issue: 1Volume: 11Pages: 63 - 72
- Distinct temporal hierarchies in membrane and cytoskeleton dynamics precede the morphological polarization of developing neurons(2014)Published in: Journal of Cell ScienceISSN: 0021-9533Issue: 20Volume: 127Pages: 4409 - 19
- Analyzing protein clusters on the plasma membrane: application of spatial statistical analyses on super-resolution microscopy images(2016)Published in: Advances in Anatomy, Embryology and Cell BiologyISSN: 0301-5556Volume: 219Pages: 95 - 122
- Gold-substituted silver-intensified peroxidase (GSSP) immunolabeling for FIB-SEM imaging(2019)Published in: Journal of Histochemistry & CytochemistryISSN: 0022-1554Issue: 5Volume: 67Pages: 351 - 360
- E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion(2017)Published in: OncotargetISSN: 1949-2553Issue: 52Volume: 8Pages: 89439 - 89450
- Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to SynapticDeficits in Fragile X Syndrome (vol 87, pg 382, 2015)(2015)Published in: NeuronISSN: 0896-6273Issue: 4Volume: 87Pages: 908 - 908
- Low hippocampal PI(4,5)P(2) contributes to reduced cognition in old mice as a result of loss of MARCKS(2013)Published in: Nature NeuroscienceISSN: 1097-6256Issue: 4Volume: 16Pages: 449
- TREM2 risk variants and associated endophenotypes in alzheimer's disease(2025)Published in: Alzheimers Research & TherapyIssue: 1Volume: 17
- N-cadherin: a new player in neuronal polarity(2012)Published in: Cell CycleISSN: 1538-4101Issue: 12Volume: 11Pages: 2223 - 4