Researcher
Frederic Rousseau
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
- See also: Frederic Rousseau (Flanders Institute for Biotechnology)
Affiliations
- Switch Laboratory (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Projects
1 - 10 of 51
- New molecular tools for diagnostic and treatment of systemic amyloidosisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Structural and morphological studies of heterotypic amyloid fibrilsFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Cotranslational protein folding and aggregationFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of Heterotypic Interactions of TDP-43 Aggregation in NeurodegenerationFrom11 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2022 → 30 Sep 2023Funding: BOF - postdoctoral mandates
- Structural dynamics basis of function in the SecB chaperoneFrom19 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Heterotypic amyloid interactions as modulators of selective cellular vulnerabilityFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 155
- Local structural preferences in shaping tau amyloid polymorphism(2024)
Authors: Grigoria Tsaka, Rodrigo Gallardo, Dietmar Thal, Frederic Rousseau, Joost Schymkowitz
- N-glycosylation as a eukaryotic protective mechanism against protein aggregation.(2024)
Authors: Bert Houben, Matthew Wilson, Joost Schymkowitz, Frederic Rousseau
Pages: eadk8173 - Modulation of hen egg white protein techno-functionality by amyloid formation(2024)
Authors: Anja Vananroye, Paula Moldenaers, Joost Schymkowitz, Frederic Rousseau, Jan Delcour
- LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons(2023)
Authors: Sofie Beckers, Katerina Konstantoulea, Maarten Dewilde, Frederic Rousseau, Joost Schymkowitz, Tom Theys, Joris de Wit, Pierre Vanderhaeghen
- Mechanisms and pathology of protein misfolding and aggregation(2023)
Authors: Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Pages: 912 - 933 - Improved coalescence and creaming stability of structured oil-in-water emulsions and emulsion gels containing ovalbumin amyloid-like fibrils produced by heat and enzymatic treatments(2023)
Authors: Frederic Rousseau, Joost Schymkowitz, Jan Delcour
- TDP‑43 pathology is associated with increased tau burdens and seeding(2023)
Authors: Sandra Oliveira Tomé, Grigoria Tsaka, Klara Gawor, Philip Van Damme, Ludo Van Den Bosch, Rik Vandenberghe, Frederic Rousseau, Joost Schymkowitz, Dietmar Thal
- Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding(2023)
Authors: Laleh Khodaparast, Ladan Khodaparast, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Frederic Rousseau, Joost Schymkowitz
- Amyloid-like p53 as prognostic biomarker in serous ovarian cancer-a study of the OVCAD consortium(2023)
Authors: Ignace Vergote, Toon Van Gorp, Frederic Rousseau, Joost Schymkowitz
Pages: 2473 - 2484 - SNPeffect 5.0: large-scale structural phenotyping of protein coding variants extracted from next-generation sequencing data using AlphaFold models(2023)
Authors: Frederic Rousseau, Joost Schymkowitz
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)