< Back to previous page
Organisation
Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven)
Division
Main organisation:Department of Oncology
Lifecycle:1 Jan 2012 → Today
Organisation profile:
The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.
Keywords:Angiogenesis
Disciplines:Morphological sciences, Oncology
Current researchers
1 - 10 of 13 results
- Max Mazzone (Responsible)
- Emanuele Berardi (Member)
- Iris Charatsidou (Member)
- João Fontela (Member)
- Linsha Ma (Member)
- Max Mazzone (Member)
- Marie-Pauline Orban (Member)
- Carla Riera Domingo (Member)
- Silvia Rivis (Member)
Projects
1 - 10 of 82
- Leveraging synthetic lethality between the Hippo and RAS-MAPK pathways to kill therapy resistant cancer cellsFrom1 Oct 2025 → TodayFunding: Foundations, funds and other with scientific goal
- Eicosanoid metabolism: uncharted territory in the immunotherapy resistance landscapeFrom1 Oct 2025 → TodayFunding: IOF - technology concept exploration
- Role of EZH2 in serine/glycine synthesis dysregulation in T-cell malignancies and opportunities for therapeutic targetingFrom3 Mar 2025 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Continued provision of an affordable medium-parametric cell analysis solution at the KU Leuven Flow Cytometry core facilityFrom1 Jan 2025 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Continued provision of an affordable medium-parametric cell analysis solution at the KU Leuven Flow Cytometry core facilityFrom1 Jan 2025 → TodayFunding: BOF - scientific equipment program
- Epigenetic regulation as a main instructor guiding tumor-associated macrophage phenotypes: can we revert the trend?From1 Jan 2025 → TodayFunding: Foundations, funds and other with scientific goal
- SETD8 as a potential therapeutic target for epigenetic re-education of tumor-associated macrophages in triple negative breast cancerFrom1 Nov 2024 → TodayFunding: FWO junior postdoctoral fellowship
- Exploiting anti-SLC4A4 nanobodies to mitigate tumor acidity and boost anticancer immunityFrom1 Sep 2024 → TodayFunding: FWO Strategic Basic Research Grant
- Targeting the DNA methylation profile of cytotoxic T cells to overcome immunotherapy resistance of pancreatic cancerFrom5 Mar 2024 → TodayFunding: Foundations, funds and other with scientific goal
- Understanding glutamate metabolism in the tumor microenvironment to tackle Immune Checkpoint Blockade (ICB) resistanceFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 334
- Lessons from the adjuvant bevacizumab trial on colon cancer: what next?(2011)Published in: JOURNAL OF CLINICAL ONCOLOGYISSN: 0732-183XIssue: 1Volume: 29Pages: 1 - 4
- Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer(2022)Published in: CANCER IMMUNOLOGY RESEARCHISSN: 2326-6066Issue: 1Volume: 10Pages: 126 - 141
- Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer(2016)Published in: GUTISSN: 0017-5749Issue: 6Volume: 65Pages: 990 - 1000
- Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study(2016)Published in: EndoscopyISSN: 0013-726XIssue: 11Volume: 48Pages: 1016 - 1022
- Myogenic induction of adult and pluripotent stem cells using recombinant proteins(2015)Published in: Biochemical and Biophysical Research CommunicationsISSN: 0006-291XIssue: 3Volume: 464Pages: 755 - 61
- Dynamic stroma reorganization drives blood vessel dysmorphia during glioma growth(2017)Published in: EMBO Molecular MedicineISSN: 1757-4676Issue: 12Volume: 9Pages: 1629 - 1645
- PHD1 regulates p53-mediated colorectal cancer chemoresistance(2015)Published in: EMBO Molecular MedicineISSN: 1757-4676Issue: 10Volume: 7Pages: 1350 - 65
- Breast tumors interfere with endothelial TRAIL at the premetastatic niche to promote cancer cell seeding(2023)Published in: Science AdvancesISSN: 2375-2548Issue: 12Volume: 9
- Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer(2019)Published in: Cell ReportsISSN: 2211-1247Issue: 1Volume: 28Pages: 104 - +
- Regulation of Blood and Lymphatic Vessels by Immune Cells in Tumors and Metastasis(2019)Published in: Annual Review of PhysiologyISSN: 0066-4278Volume: 81Pages: 535 - 560