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Researcher
Bert Vanmechelen
- Disciplines:Microbiology, Immunology
Affiliations
- Virology, Antiviral Drug & Vaccine Research Group (Division)
Member
From1 Jul 2024 → Today - Laboratory of Clinical and Epidemiological Virology (Rega Institute) (Division)
Member
From1 Nov 2016 → 30 Jun 2024
Projects
1 - 6 of 6
- Correlates of Immunity to filovirus infectionFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Discovery and in-depth characterization of paramyxovirusesFrom1 Nov 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploration of unknown viruses in Belgian ticksFrom5 Oct 2022 → 10 Apr 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- The construction of biologically contained filovirus systems and their purposes in antiviral compound screening and receptor binding associated studies.From18 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Characterizing the virus diversity in Belgian and European batsFrom1 Oct 2021 → 30 Sep 2022Funding: BOF - postdoctoral mandates
- Development and application of filovirus reverse genetics systems for antiviral compound screeningFrom1 Jan 2017 → 24 Sep 2021Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 51
- Annual (2024) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota).(2025)Published in: Journal of General VirologyISSN: 0022-1317Issue: 6Volume: 106
- A guanidine-based coronavirus replication inhibitor which targets the nsp15 endoribonuclease and selects for interferon-susceptible mutant viruses(2025)Published in: PLoS PathogensISSN: 1553-7366Issue: 2Volume: 21
- A retrospective genomic characterisation of the 2022 mpox outbreak in Belgium, and in vitro assessment of three antiviral compounds(2024)Published in: EBioMedicineISSN: 2352-3964Volume: 110
- Generation of Biologically Contained Marburg Virus.(2024)Pages: 155 - 164
- Emergence of the B.1.214.2 SARS-CoV-2 lineage with an Omicron-like spike insertion and a unique upper airway immune signature(2024)Published in: BMC Infectious DiseasesISSN: 1471-2334Issue: 1Volume: 24
- Multicenter benchmarking of short and long read wet lab protocols for clinical viral metagenomics(2024)Published in: JOURNAL OF CLINICAL VIROLOGYISSN: 1386-6532Volume: 173
- Design and validation of a laboratory-developed diagnostic assay for monkeypox virus(2023)Published in: Virus GenesISSN: 0920-8569Issue: 6Volume: 59Pages: 795 - 800
- Discovery and genome characterization of six new orthoparamyxoviruses in small Belgian mammals(2023)Published in: Virus EvolutionISSN: 2057-1577Issue: 2Volume: 9
- Immunovirological and environmental screening reveals actionable risk factors for fatal COVID-19 during post-vaccination nursing home outbreaks(2023)Published in: Nat AgingISSN: 2662-8465Issue: 6Volume: 3Pages: 722 - 733
- The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir(2023)Published in: mBioISSN: 2150-7511Issue: 1Volume: 14