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Researcher
Veerle Janssens
- Disciplines:Proteins, Cell division, Cell signalling, Posttranslational modifications, Cancer biology, Cancer therapy, Developmental biology, Genetics
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Responsible
From1 Oct 2021 → Today - Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 23
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Integrated, multimodal phenotypic analysis of Ppp2r1a knockin mice: new in vivo models of syndromic PP2A-related (neuro)developmental disorders.From1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Insights into the disease mechanisms of PPP2R5D, PPP2R5C and PPP2R1A syndromes: towards therapeutic avenuesFrom1 Jul 2021 → TodayFunding: Foreign private sponsor - undefined
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom22 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R1A as a new biomarker in type-II endometrial cancers.From1 Jan 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R5D-related neurodevelopmental disorders: pathologic mechanisms and therapeutic avenuesFrom14 Sep 2020 → 15 Feb 2023Funding: Foundations, funds and other with scientific goal
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatmentFrom1 Jan 2019 → 15 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Function and post-translational regulation of the PP2A methylesterase PME-1 in the cellular response to stress conditionsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- 3-year-research proposal, submitted 1 Nov 2018 to JORDAN'S GUARDIAN ANGELS FOUNDATION-by prof.dr. Veerle Janssens (KU Leuven, Leuven, Belgium)From1 Jul 2018 → 30 Jun 2021Funding: Foreign private sponsor - undefined
Publications
1 - 10 of 83
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatment(2023)
Authors: Liesbeth Guffens, Veerle Janssens, Rita Derua
- Targeting radiotherapy resistance in Head and Neck Cancers: the potential biomarker role of TIPRL1 and CIP2A, two cellular inhibitors of Protein Phosphatase 2A(2023)
Authors: Célie Cokelaere, Veerle Janssens, Rita Derua, Sandra Nuyts
- TIPRL1 and its ATM‑dependent phosphorylation promote radiotherapy resistance in head and neck cancer(2023)
Authors: Célie Cokelaere, Rüveyda Dok, Emanuela Elsa Cortesi, Anna Sablina, Sandra Nuyts, Rita Derua, Veerle Janssens
- PME-1-regulated neural cell death: new therapeutic opportunities?(2023)
Authors: Liesbeth Guffens, Rita Derua, Veerle Janssens
Pages: 11694 - 11696 - The tumor suppressive role of Protein Phosphatase 2A B56δ subunit in primary liver cancer(2023)
Authors: Judit Domènech Omella, Veerle Janssens
- Editorial: Deciphering the etiology of rare genetic disorders associated with protein phosphatases(2023)
Authors: Veerle Janssens
- A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d(2023)
Authors: Judit Domènech Omella, Emanuela Elsa Cortesi, Iris Verbinnen, Michiel Remmerie, Tania Roskams, Veerle Janssens
- PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling(2023)
Authors: Liesbeth Guffens, Rita Derua, Veerle Janssens
- Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality.(2023)
Authors: Jos van Pelt, Rita Derua, Liesbeth Guffens, Veerle Janssens, Chris Verslype
- C-glycosides analogues of the okadaic acid central fragment exert neuroprotection via restoration of PP2A-phosphatase activity: A rational design of potential drugs for Alzheimer?s disease targeting tauopathies(2023)
Authors: Veerle Janssens
Patents
1 - 2 of 2
- Pro-apoptotic set and pp2a peptides (Inventor)
- Pro-apoptotic set and pp2a peptides (Inventor)