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Researcher
Mark Waer
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Department of Microbiology, Immunology and Transplantation (Department)
Member
From1 Oct 2016 → Today - Tracheal Transplantation (Lab)
Member
From1 Oct 2005 → 30 Sep 2016 - Nephrology and Renal Transplantation Research Group (Division)
Member
From1 Oct 1999 → 30 Sep 2005
Projects
1 - 10 of 11
- Immunosuppressive effects of a CD4 receptor down-modulator: in vitro study of the signal peptide-dependent ER translocation inhibitor cyclotriazadisulfonamide (CADA)From1 Oct 2014 → 26 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Proteomics analysis for the identification of candidate protective proteins against sepsisFrom1 Oct 2014 → 16 Nov 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- "BD FACS Verse" Flow Cytometer.From16 Apr 2012 → 25 Oct 2018Funding: Hercules - Small and Medium size research infrastructure
- Identification of new immunomodulating targets and agents for B lymphocytesFrom1 Oct 2011 → 7 Jun 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- How does 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) act on immune cells during autoimmunity?From1 Dec 2010 → 30 Sep 2013Funding: BOF - Doctoral projects
- FACS Cell sorter (FACSAriaII), central to the establishment of a K.U.Leuven FACS core Facility.From22 Jul 2010 → 21 Jan 2017Funding: Hercules - Small and Medium size research infrastructure
- Recipient-mediated antileukemic effects after allogeneic hematopoietic stem cell transplantation: studies in mice.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Molecular modeling, synthesis and biological evaluation of human amino-acyltRNA synthetase inhibitors as immunosuppressive agents.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Beckman Coulter Gallios flowcytometer.From20 Oct 2008 → 19 Apr 2015Funding: Hercules - Small and Medium size research infrastructure
- The marginal zone B cel in concordant xenograft rejection: critical help signals in the T cel-independent type II xenoantibody response and possible targets for xeno-immunosuppression.From1 Oct 2008 → 30 Sep 2013Funding: FWO fellowships
Publications
1 - 10 of 66
- 3-nitropyridine analogues as novel microtubule-targeting agents(2024)Published in: Plos OneISSN: 1932-6203Issue: 11Volume: 19
- Synthesis of mizoribine prodrugs and their in vivo evaluation as immunosuppressive agents(2023)Published in: Bioorganic & Medicinal Chemistry LettersISSN: 0960-894XVolume: 95
- Establishment of operational tolerance to sustain antitumor immunotherapy(2022)Published in: JOURNAL OF HEART AND LUNG TRANSPLANTATIONISSN: 1053-2498Issue: 5Volume: 41Pages: 568 - 577
- Small Molecule Cyclotriazadisulfonamide Abrogates the Upregulation of the Human Receptors CD4 and 4-1BB and Suppresses In Vitro Activation and Proliferation of T Lymphocytes(2021)Published in: Frontiers in ImmunologyISSN: 1664-3224Volume: 12
- Immunization with alloantibodies-covered melanoma cells induces regional antitumor effects that become systemic when combined with 5-FU treatment(2021)Published in: Cancer LettersISSN: 0304-3835Volume: 503Pages: 151 - 162
- Intratumoral immunotherapy with anti-PD-1 and TLR9 agonist induces systemic antitumor immunity without accelerating rejection of cardiac allografts(2021)Published in: AMERICAN JOURNAL OF TRANSPLANTATIONISSN: 1600-6135Issue: 1Volume: 21Pages: 60 - 72
- Donor Lymphocyte-Derived Natural Killer Cells Control MHC Class I-Negative Melanoma(2020)Published in: CANCER IMMUNOLOGY RESEARCHISSN: 2326-6066Issue: 6Volume: 8Pages: 756 - 768
- Improved Anti-Tumour Adaptive Immunity Can Overcome the Melanoma Immunosuppressive Tumour Microenvironment(2019)Published in: CancersISSN: 2072-6694Issue: 11Volume: 11
- Immunosuppressive effects of a CD4 receptor down-modulator: in vitro study of the signal peptide-dependent ER translocation inhibitor cyclotriazadisulfonamide (CADA)(2019)
- Solid Tumor-Induced Immune Regulation Alters the GvHD/GvT Paradigm after Allogenic Bone Marrow Transplantation(2019)Published in: CANCER RESEARCHISSN: 0008-5472Issue: 10Volume: 79Pages: 2709 - 2721
Patents
1 - 8 of 8
- Novel prodrugs of mizoribine
- Autoimmune and inflammatory disorder therapy
- Novel prodrugs of mizoribine
- Purine analogues and their use as immunosuppressive agents
- Autoimmune and inflammatory disorder therapy
- Thiazolopyrimidine modulators as immunosuppressive agents
- Thiazolopyrimidine modulators as immunosuppressive agents
- THIAZOLOPYRIMIDINE MODULATORS AS IMMUNOSUPPRESSIVE AGENTS