Researcher
Francis Impens
- Keywords (Ghent University):post-translational modifications, proteomics, listeria, host-pathogen interactions
- Disciplines (Flanders Institute for Biotechnology):Analytical biochemistry, Cell death and senescence, Analysis of next-generation sequence data, General diagnostics, (Bio)molecular modelling and design, Auto-ecology, Biogeography and phylogeography, Anthropological genetics, Bacteriology, Epigenomics, Environmental safety and health of nanotechnology, Medical biophysics, Adaptive immunology, Cell death, Behavioural neuroscience, Cancer biology
- Disciplines (Ghent University):Infectious diseases, Proteomics, Posttranslational modifications, Proteins, Medical proteomics
- See also: Francis Impens (Flanders Institute for Biotechnology)
Affiliations
- VIB-UGent Center for Medical Biotechnology (Research Center)
Responsible
From1 Oct 2021 → Today - VIB Proteomics Core (Core Lab)
Responsible
From1 Oct 2021 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Impens Lab (Research group)
Responsible
From1 Jan 2017 → Today - VIB Proteomics Core (Core Lab)
Responsible
From1 Jan 2017 → Today - Department of Biochemistry (Department)
Member
From1 Oct 2005 → 30 Sep 2018
Projects
1 - 10 of 10
- Characterizing ISG15 conjugation as a molecular signal for protein oligomerization and translocation in host immunityFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Vaccine-induced and ISG15-mediated immune responses to Bacterial Infection and Moyamoya DiseaseFrom1 Dec 2022 → TodayFunding: BOF - projects
- BOF ZAP human cellular biochemistryFrom1 Sep 2022 → TodayFunding: BOF - ZAP BOF mandates
- Improved data-driven bioinformatics tools to greatly extend neo- and xeno-epitope landscapes detected by immunopeptidomics.From1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- Exploring nanobodies against Interferon Stimulated Gene 15 (ISG15) to combat autoimmune and infectious diseases.From1 Nov 2020 → TodayFunding: FWO fellowships
- Investigating the effects of regulatory phosphorylation and linear ubiquitination on Pyrin-mediated auto-inflammatory disorders.From1 Oct 2019 → TodayFunding: BOF - projects
- Neuro-TRAFFIC: Integrated platform to validate vesicular trafficking-associated processes in neurodegenerative diseasesFrom1 Jun 2017 → 31 May 2021Funding: FWO Strategic Basic Research (SBO)
- 'BacVirISG15' - in the framework of ERA-NET Infect-ERA JTC 2016. The Interferon Stimulated Gene 15 (ISG15) modification system in host pathogen interactions: mechanisms, technology and translational potential.From1 Apr 2017 → 31 Mar 2020Funding: FWO research project (including WEAVE projects)
- Odysseus F. Impens: Proteomics-based characterization of the protein interplay between pathogenic bacteria and their hostFrom1 Oct 2016 → 30 Sep 2021Funding: BOF - Doctoral projects
Publications
1 - 10 of 50
- SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains(2024)
Authors: Arne Janssens, Van Son Nguyen, Adam J Cecil, Sander E Van der Verren, Evy Timmerman, Michaël Deghelt, Alexander J Pak, Jean-François Collet, Francis Impens, Han Remaut
Pages: 617 - 625 - Revealing the transitory and local effect of zebularine on development and on proteome dynamics of Salix purpurea(2024)
Authors: Andrea Pagano, Carolina Gomes, Evy Timmerman, Paweł Sulima, Jerzy Andrzej Przyborowski, Dariusz Kruszka, Francis Impens, Jorge Almiro Pinto Paiva
- Proteomics-based analysis and diagnosis of formalin-fixed paraffin-embedded amyloidosis samples(2023)Series: Methods in Molecular Biology
Authors: Delphi Van Haver, Amélie Dendooven, Francis Impens
Pages: 213 - 233 - Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage(2023)
Authors: Lore Billiet, Laurenz De Cock, Guillem Sanchez Sanchez, Rupert Mayer, Glenn Goetgeluk, Stijn De Munter, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, et al.
- Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis(2023)
Authors: Benjamin Cappe, Mike Vadi, Eliza Sack, Ludivine Wacheul, Bruno Verstraeten, Sara Dufour, Julien Franck, Wei Xie, Francis Impens, An Hendrix, et al.
- Spatial mechano-signaling regulation of GTPases through non-degradative ubiquitination(2023)
Authors: Raj N Sewduth, Paolo Carai, Tonci Ivanisevic, Mingzhen Zhang, Hyunbum Jang, Benoit Lechat, Delphi Van Haver, Francis Impens, Ruth Nussinov, Elizabeth Jones, et al.
- The extracellular matrix dictates regional competence for tumour initiation(2023)
Authors: Nordin Bansaccal, Pauline Vieugue, Rahul Sarate, Yura Song, Esmeralda Minguijon, Yekaterina A Miroshnikova, Dagmar Zeuschner, Amandine Collin, Justine Allard, Dan Engelman, et al.
Pages: 828 - 835 - CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity(2023)
Authors: W Guo, H Wang, A Kumar Tharkeshwar, J Couthouis, E Braems, P Masrori, E Van Schoor, Y Fan, K Ahuja, M Moisse, et al.
Pages: 1245 - 1259 - RHOJ controls EMT-associated resistance to chemotherapy(2023)
Authors: M Debaugnies, S Rodríguez-Acebes, J Blondeau, MA Parent, M Zocco, Y Song, V de Maertelaer, V Moers, M Latil, C Dubois, et al.
Pages: 168 - 175 - The nutritional composition and cell size of microbial biomass for food applications are defined by the growth conditions(2023)
Authors: Myrsini Sakarika, Frederiek-Maarten Kerckhof, Lotte Van Peteghem, Alexandra Pinto Martins Pereira, Tim Van Den Bossche, Robbin Bouwmeester, Ralf Gabriels, Delphi Van Haver, Barbara Ulčar, Lennart Martens, et al.