Researcher

Sophie Gryseels

Research Expertise:I study the evolutionary dynamics of viruses and their hosts. I am interested in unraveling evolutionary histories of pathogens by using archived samples from which we can characterize historical virus genomes. By comparing these evolutionary histories with the diversity, genealogy and ecology of the natural hosts, in particular mammals, I aim to better understand the drivers and constraints of viral evolution imposed by the hosts.

Keywords:SEQUENCE ANALYSIS, LANDSCAPE ECOLOGY, SEQUENCING, VIRUS, PHYLOGENETICS, EVOLUTION, EVOLUTIONARY ECOLOGY, DIAGNOSTICS FOR INFECTIOUS DISEASES, Biology

Disciplines:Animal biology, Bioinformatics and computational biology, Ecology, Evolutionary biology, General biology, Genetics, Microbiology, Molecular and cell biology, Animal genetics, Population, ecological and evolutionary genetics, Infectious diseases, Analysis of next-generation sequence data, Computational evolutionary biology, comparative genomics and population genomics, Virology, Bioinformatics of disease

Research techniques:- molecular biology techniques in the laboratory to determine genetic sequences of the organisms (mainly viruses, bacteria, arthropods and vertebrates) we study (DNA/RNA extraction, reverse transcription, PCR, Sanger Sequencing, Nanopore sequencing, Illumina sequencing). - computational analyses of RNA and DNA sequence data (genome assemblies, phylogenetics, population genetics). - statistics of ecological observational data

Users of research expertise:Researchers and others who need to identify species and genotype organisms.