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Researcher
Patrick Pauwels
- Research Expertise:molecular oncopathology
- Keywords:ANATOMOPATHOLOGY, ONCOLOGY, Medicine
- Disciplines:Oncology not elsewhere classified
- Research techniques:Next gen seq, ddPCR, liquid and tissue biopsy NGS, immunohistochemie, FISH, organoids
- Users of research expertise:researchers in de field of oncology
Affiliations
- Center for Oncological Research (CORE) (Research group)
Member
From1 Oct 2023 → Today - Center for Oncological Research (CORE) (Research group)
Member
From1 Jan 2019 → 30 Sep 2023 - Molecular Imaging, Pathology, Radiotherapy & Oncology (MIPRO) (Research group)
Member
From1 Oct 2009 → 31 Dec 2018
Projects
1 - 10 of 34
- RNA Processing for anti-cancer immunotherapy (CANCERNA).From1 Jun 2022 → 31 May 2025Funding: HORIZON.2.1 - Health
- Biobank Antwerp.From1 Jan 2022 → TodayFunding: BOF - research organisations
- Development of an innovative personalised CAR-NK cell therapy for pancreatic cancer.From1 Jan 2022 → TodayFunding: BOF - projects
- A novel photoelectrochemical detection technology for molecular cancer biomarkers.From1 Sep 2021 → 31 Oct 2022Funding: IOF - technology validation in lab
- Combining targeted therapy and immunotherapy to improve survival and quality of life of head and neck cancer patients.From1 Mar 2021 → 28 Feb 2025Funding: Nonprofit institution or equivalents
- Heterogeneity of HER2 amplification in breast cancer – the use of liquid biopsy to identify patients with discrepancies between primary tumor and metastatic lesionsFrom3 Mar 2020 → 2 Mar 2022Funding: Nonprofit institution or equivalents
- Leveraging patient-driven research to improve rational therapy selection in (ROS1+) non-small cell lung cancer.From1 Jan 2020 → 31 Dec 2021Funding: FWO Humanitarian research project Stand up against Cancer
- Urine as a liquid biopsy for early stage cancer detection.From1 Jan 2020 → 31 Dec 2023Funding: Baekeland
- Integrated Personalized & Precision Oncology Network (IPPON).From1 Jan 2020 → TodayFunding: BOF - research organisations, Fund Recuperation Fiscal Exemption
- Preclinical investigation of immunotherapy and VEGF-targeted therapy in combination with voluntary exercise as novel treatment strategy for malignant pleural mesothelioma.From1 Nov 2019 → 31 Oct 2024Funding: Nonprofit institution or equivalents
Publications
1 - 10 of 250
- CD70-directed CAR natural killer cells as novel off-the-shelf cell therapy in colorectal and pancreatic cancer targeting tumor cells and their microenvironment(2025)Number of pages: 222
- Small airways disease in pre-COPD with emphysema: a cross-sectional study(2024)Published in: American journal of respiratory and critical care medicineISSN: 1073-449XVolume: 209Pages: 683 - 692
- Preclinical evaluation of CDK4 phosphorylation predicts high sensitivity of pleural mesotheliomas to CDK4/6 inhibition(2024)Published in: Molecular OncologyISSN: 1574-7891Volume: 18Pages: 866 - 894
- IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts(2024)Published in: Journal of hematology and oncologyISSN: 1756-8722Volume: 17Pages: 1 - 19
- Urine biomarkers in cancer detection: a systematic review of preanalytical parameters and applied methods(2023)Published in: International journal of cancerISSN: 0020-7136Volume: 152Pages: 2186 - 2205
- Targeting CD70 in combination with chemotherapy to enhance the anti-tumor immune effects in non-small cell lung cancer(2023)Published in: OncoimmunologyISSN: 2162-4011Volume: 12Pages: 1 - 11
- PD-1, PD-L1, IDO, CD70 and microsatellite instability as potential targets to prevent immune evasion in sarcomas(2023)Published in: ImmunotherapyISSN: 1750-743XVolume: 15Pages: 1257 - 1273
- Urine as a liquid biopsy for cancer detection(2023)Number of pages: 265
- Protein biomarker discovery studies on urinary sEV fractions separated with UF-SEC for the first diagnosis and detection of recurrence in bladder cancer patients(2023)Published in: BiomoleculesISSN: 2218-273XVolume: 13Pages: 1 - 26
- Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs(2023)Published in: Clinical epigeneticsISSN: 1868-7075Volume: 15Pages: 1 - 14