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Researcher
Jim Baggen
- Disciplines:Molecular and cell biology, Oncology
Affiliations
- Molecular Genetics and Therapeutics in Virology and Oncology Research Group (Division)
Member
From1 Jun 2024 → Today - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Apr 2018 → Today
Projects
1 - 5 of 5
- Exploring host-virus dynamics in emerging zoonotic viruses: A proviral host factor approachFrom7 Aug 2025 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Uncovering kinase inhibitor resistance mechanisms via CRISPR-based mutagenesis screeningFrom1 Jan 2025 → TodayFunding: FWO research project (including WEAVE projects)
- Identification of proviral host factor combinations as drug targets for viruses with pandemic potentialFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Multiplex CRISPR screening to identify drug target combinations for antiviral therapyFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Breaking cancer drug resistance: exploring drug resistance mechanisms to exploit associated vulnerabilitiesFrom1 Jul 2020 → 30 Jun 2021Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 15
- TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry(2023)Published in: CellISSN: 0092-8674Issue: 16Volume: 186Pages: 3427 - +
- Antiviral strategies against (non-polio) picornaviruses(2021)Pages: 347 - 365
- Cellular host factors for SARS-CoV-2 infection(2021)Published in: Nature MicrobiologyISSN: 2058-5276Issue: 10Volume: 6Pages: 1219 - 1232
- Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2(2021)Published in: Nature GeneticsISSN: 1061-4036Issue: 4Volume: 53Pages: 435 - +
- Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence(2019)Published in: Emerging Microbes & infectionsISSN: 2222-1751Issue: 1Volume: 8Pages: 1076 - 1085
- Bypassing pan-enterovirus host factor PLA2G16(2019)Published in: NATURE COMMUNICATIONSISSN: 2041-1723Issue: 1Volume: 10
- Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus(2019)Published in: mBioISSN: 2150-7511Issue: 4Volume: 10
- The life cycle of non-polio enteroviruses and how to target it(2018)Published in: Nature Reviews. MicrobiologyISSN: 1740-1526Issue: 6Volume: 16Pages: 368 - 381
- The life cycle of non-polio enteroviruses and how to target it (vol 16, pg 368, 2018)(2018)Published in: Nature Reviews. MicrobiologyISSN: 1740-1526Issue: 6Volume: 16Pages: 391 - 391
- Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus(2018)Published in: Proceedings of the National Academy of Sciences of the United States of AmericaISSN: 0027-8424Issue: 2Volume: 115Pages: 397 - 402