Researcher
Jim Baggen
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Apr 2018 → Today
Projects
1 - 3 of 3
- Identification of proviral host factor combinations as drug targets for viruses with pandemic potentialFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Multiplex CRISPR screening to identify drug target combinations for antiviral therapyFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Breaking cancer drug resistance: exploring drug resistance mechanisms to exploit associated vulnerabilitiesFrom1 Jul 2020 → 30 Jun 2021Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 15
- TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry(2023)
Authors: Jim Baggen, Maarten Jacquemyn, Els Vanstreels, Hendrik Jan Thibaut, Piet Maes, Dirk Daelemans
Pages: 3427 - + - Antiviral strategies against (non-polio) picornaviruses(2021)
Authors: Rana Abdelnabi, Jim Baggen, Johan Neyts
Pages: 347 - 365 - Cellular host factors for SARS-CoV-2 infection(2021)
Authors: Jim Baggen, Els Vanstreels, Sander Jansen, Dirk Daelemans
Pages: 1219 - 1232 - Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2(2021)
Authors: Jim Baggen, Els Vanstreels, Sander Jansen, Bram Boeckx, Vincent Geudens, Dirk Jochmans, Joost Wauters, Els Wauters, Bart Vanaudenaerde, Diether Lambrechts, et al.
Pages: 435 - + - Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence(2019)
Authors: Jim Baggen, Pieter Leyssen, Erik Verbeken, Johan Neyts, Hendrik Jan Thibaut
Pages: 1076 - 1085 - Bypassing pan-enterovirus host factor PLA2G16(2019)
Authors: Jim Baggen, Yue Liu, Heyrhyoung Lyoo, Arno LW van Vliet, Maryam Wahedi, Jost W de Bruin, Richard W Roberts, Pieter Overduin, Adam Meijer, Michael G Rossmann, et al.
- Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus(2019)
Authors: Jim Baggen, Hendrik Jan Thibaut
- The life cycle of non-polio enteroviruses and how to target it(2018)
Authors: Jim Baggen, Hendrik Jan Thibaut, Jeroen RPM Strating, Frank JM van Kuppeveld
Pages: 368 - 381 - The life cycle of non-polio enteroviruses and how to target it (vol 16, pg 368, 2018)(2018)
Authors: Jim Baggen, Hendrik Jan Thibaut, Jeroen RPM Strating, Frank JM van Kuppeveld
Pages: 391 - 391 - Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus(2018)
Authors: Jim Baggen, Daniel L Hurdiss, Georg Zocher, Nitesh Mistry, Richard W Robert, Jasper J Slager, Hongbo Guo, Arno LW van Vliet, Maryam Wahedi, Kimberley Benschop, et al.
Pages: 397 - 402