Research services to complete a project entitled "21st Century Treatments for Sustainable Elimination of Leishmaniasis – Part 2" (LeishNCE2). (LeishNCE2)

The collaboration with DNDi is aimed at providing a solid proof-of-concept in in vitro and animal models for the treatment of leishmaniasis with current (pre-)clinical leads and/or with a combination of leads and current reference antileishmanial drugs. Services to support DNDi discovery and development projects will cover in vitro monotherapy profiling against a panel of (resistant) strains, in vivo evaluation in mouse and/or hamster efficacy models including both monotherapy and combination therapy with PK analysis, evaluation of antiparasitic killing kinetics, and evaluation in immunocompromised animal models.

Keywords:PARASITOLOGY

Disciplines:Parasitology, In vitro testing, Non-clinical studies, Drug discovery and development not elsewhere classified

Project type:Service project