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Organisation
VANDENBROUCKE LAB
Research group
Main organisation:VIB-UGENT CENTER FOR INFLAMMATION RESEARCH
Lifecycle:1 Mar 2018 → Today
Organisation profile:Research on the effect of systemic inflammation (including sepsis/SIRS or other inflammatory stimuli such as (inflamm)aging) and neuroinflammation (such as the age-related diseases Alzheimer's and Parkinson's disease) on the blood-CSF barrier.
Keywords:Immunology, Infection innate immunity, inflammation, autoimmunity
Disciplines:Bioinformatics and computational biology, Immunology, Microbiology
Current researchers
1 - 10 of 29 results
- Fatemeh Afsharnoori (Member)
- Jonas Castelein (Member)
- Lien Cools (Member)
- Clint De Nolf (Member)
- Hilke De Rouck (Member)
- Nell De Ruysscher (Member)
- Lize De Vlieger (Member)
- Chirantan Debnath (Member)
- Kyra Defourny (Member)
- Pieter Dujardin (Member)
Projects
1 - 10 of 12
- Deciphering how Akkermansia muciniphila elicits beneficial effects in Alzheimer's disease.From1 Jan 2025 → TodayFunding: Private funding of national origin - undefined
- Extracellular vesicles as putative link between respiratory virus infection and brain disease.From1 Aug 2024 → TodayFunding: Other international institutions, not mentioned elsewhere
- ExPa"D": Extracellular vesicle biology in Parkinsonian disordersFrom1 Jul 2024 → TodayFunding: Other international institutions, not mentioned elsewhere
- Drug DELIvery to the brain via CHOroid Plexus targeting.From1 Mar 2024 → TodayFunding: HORIZON.1.1 - European Research Council (ERC)
- Immune profiling of Alzheimer's brain to pave the way for novel treatments.From1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Investigating the biomarker potential and pathological role of bacterial extracellular vesicles in Alzheimer's disease.From1 Jan 2023 → TodayFunding: Private funding of national origin - undefined
- VIB Grant for Vandenbroucke Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- A three-arm combination immunotherapy against Alzheimer’s diseaseFrom1 Jan 2021 → 31 Dec 2023Funding: Private funding of national origin - undefined
- Investigation of the therapeutic applicability of IL1R and TNFR1 blockage in Alzheimer's diseaseFrom1 Jan 2019 → 31 Dec 2020Funding: Private funding of national origin - undefined
- Choroid plexus-derived extracellular vesicles in Alzheimer's diseaseFrom1 Jan 2018 → 31 Dec 2019Funding: Private funding of national origin - undefined
Publications
1 - 10 of 73
- Choroid plexus-derived miR-204 regulates the number of quiescent neural stem cells in the adult brain.(2019)Published in: EMBO journalVolume: 38Pages: e100481
- Involvement of the Choroid Plexus in the Pathogenesis of Niemann-Pick Disease Type C.(2021)Published in: Frontiers in cellular neuroscienceVolume: 15Pages: 757482
- A New Venue of TNF Targeting(2018)Published in: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESVolume: 19Pages: piiE1442
- Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer's disease.(2022)Published in: Advanced drug delivery reviewsVolume: 190Pages: 114486
- Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury.(2020)Published in: GliaVolume: 68Pages: 2643-2660
- Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors.(2025)Published in: Nature communicationsVolume: 16Pages: 4028
- Importance of extracellular vesicle secretion at the blood-cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.(2021)Published in: Acta neuropathologica communicationsVolume: 9Pages: 143
- Involvement of the choroid plexus in Alzheimer's disease pathophysiology: findings from mouse and human proteomic studies.(2024)Published in: Fluids and barriers of the CNSVolume: 21Pages: 58
- The power of imaging to understand extracellular vesicle biology in vivo.(2021)Published in: Nature methodsVolume: 18Pages: 1013-1026
- Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies.(2025)Published in: Neural regeneration researchVolume: 20Pages: 3461-3475