MAINTAINING REGULATORY T CELL (Treg) FUNCTIONALITY UNDER CONDITIONS TRIGGERING Treg DYSFUNCTIONALITY

The invention relates to protecting regulatory T cells (Tregs) against dysfunctionality as caused in e.g. auto-immune disease settings. In particular, such protection is warranted in case of adoptive transfer or Tregs as a means of treatment of auto-immune and other diseases, and as a means of controlling transplant or graft rejection. Furthermore in particular, the protection is enabled by inhibiting the Treg mitochondrial sodium/lithium/calcium exchanger.

Patent Publication Number: WO2024156726

Source: USPTO,

Year filing: 2024

Year approval: 2025

Year publication: 2024

Status: Requested

Technology domains: undefined

Validated for IOF-key: Yes

Attributed to: Association University - Colleges Limburg