Image analysis platform for users of the GLiM core facility

The Ghent Light Microscopy (GLiM) Core Facility offers access to advanced light microscopy techniques for researchers of UGent and beyond. Light microscopy plays an indispensable role in life science research, providing information on how living cells and organisms function under relevant conditions. In addition to sample preparation and image acquisition, analyzing the obtained images to extract quantitative data is an essential part of the scientific workflow. Currently, GLiM users must rely on freeware solutions with limited capabilities and poor user-friendliness. To support its users across the entire microscopy workflow, GLiM requests an advanced image processing platform in this project application. By integrating a robust software solution within the GLiM Core Facility, we aim to provide accessible, workflow-driven image analysis that facilitates efficient data processing. The proposed infrastructure will support comprehensive imaging analysis tools, including preprocessing, segmentation, quantification, AI-driven enhancements, and batch processing. The software will be implemented within the GLiM Core Facility, ensuring widespread accessibility for researchers at Ghent University as well as for external users. The infrastructure will also support educational activities, such as the doctoral school specialist course on Advanced Light and Fluorescence Microscopy organized by GLiM each year. By making an advanced, intuitive image analysis platform available through GLiM, we enable high-quality, reproducible scientific research and remove technical barriers in microscopy-based investigations.