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Researcher
De Wit Joris
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Cell signalling, Intracellular compartments and transport, Membrane structure and transport, Cognitive neuroscience, Developmental neuroscience, Neurological and neuromuscular diseases
- See also: Joris de Wit (KU Leuven)
Affiliations
- Laboratory of Synapse Biology (VIB-KU Leuven) (Lab)
Responsible
From1 Jan 2013 → Today - Laboratory of Synapse Biology (VIB-KU Leuven) (Lab)
Member
From1 Jan 2017 → Today - DE WIT LAB (Research group)
Responsible
From1 Jan 2017 → Today - Department of Human Genetics (Department)
Member
From1 Jan 2013 → 31 Dec 2016
Projects
1 - 10 of 11
See also Joris de Wit for projects of KU Leuven.
Here below the projects of Flanders Institute for Biotechnology.
- Synaptic signatures: Understanding thalamocortical circuit specification and disease vulnerabilityFrom1 Apr 2025 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- From proteins to circuits: understanding thalamocortical circuit vulnerability in autism (SFARI-Pilot)From1 May 2024 → TodayFunding: Other international institutions, not mentioned elsewhere
- Early vulnerability in Alzheimer’s disease of a peptidergic system regulating neuronal activity and sleepFrom1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- The therapeutic potential of neuronal Brinp2 in ameliorating Alzheimer's Disease symptoms by increasing lysosomal exocytosisFrom1 Jan 2024 → TodayFunding: Private funding of national origin - undefined
- Microglia-synapse molecular interactions in neurodegenerative disorders (Marie curie individual fellowship Teun Klein Gunnewiek )From1 May 2022 → 30 Apr 2024Funding: Other EU initiatives out of framework
- VIB Grant for de Wit Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- The role of pore forming protein family member Brinp2 in neuron development and function (Beurs voor Marinka Brouwer)From1 Jul 2021 → 30 Jun 2023Funding: Other international institutions, not mentioned elsewhere
- EC-CA1 network dysfunction in Alzheimer's disease (Calafate, Sara)From1 Oct 2018 → 30 Sep 2022Funding: Other international institutions, not mentioned elsewhere
- Dissecting a pathological framework for Alzheimer’s disease at the circuit-levelFrom1 Jan 2018 → 31 Dec 2019Funding: Private funding of national origin - undefined
- Selective vulnerability of interneurons in Alzheimer’s diseaseFrom1 Jan 2017 → 31 Dec 2018Funding: Private funding of national origin - undefined
Publications
1 - 10 of 34
See also Joris de Wit for publications of KU Leuven.
Here below the publications of Flanders Institute for Biotechnology.
- Enhancer-driven cell type comparison reveals similarities between the mammalian and bird pallium.(2025)Published in: Science (New York, N.Y.)Volume: 387Pages: eadp3957
- Synaptic signatures and disease vulnerabilities of layer 5 pyramidal neurons.(2025)Published in: Nature communicationsVolume: 16Pages: 228
- LRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface.(2024)Published in: Nature communicationsVolume: 15Pages: 8807
- Protocol to process fresh human cerebral cortex biopsies for patch-clamp recording and immunostaining.(2024)Published in: STAR protocolsVolume: 5Pages: 103313
- The autism susceptibility kinase, TAOK2, phosphorylates eEF2 and modulates translation.(2024)Published in: Science advancesVolume: 10Pages: eadf7001
- Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.(2024)Published in: Science (New York, N.Y.)Volume: 384Pages: eadd6260
- Cell Adhesion Molecule Signaling at the Synapse: Beyond the Scaffold.(2024)Published in: Cold Spring Harbor perspectives in biologyVolume: 16Pages: a041501
- Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer's disease.(2023)Published in: Nature neuroscienceVolume: 26Pages: 1021-1031
- LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.(2023)Published in: CellVolume: 186Pages: 5766-5783
- Proteomics-based synapse characterization: From proteins to circuits.(2023)Published in: Current opinion in neurobiologyVolume: 79Pages: 102690