Projects

A professorship granted by the Special Research Fund is a primarily research-oriented position and is made available for excellent researchers with a high-quality research programme.

Despite great achievements in medicine, infectious diseases are still a leading cause of children morbidity and mortality. Up until now, most vaccines have been empirically generated without a true understanding of the precise immunologic mechanisms of action of successful vaccines. As we are now facing difficulties in developing new or more efficient vaccines, we need to understand the precise mechanisms underlying ...

Recent advances in systems biology have transformed our understanding of human immunology, still our understanding of vaccine-induced immune responses remains limited. However, the use of systems vaccinology in clinical vaccine research shows great promise in unravelling molecular mechanisms of action of novel vaccines and adjuvants to induce protective immunity. Moreover, it allows for detailed investigations in how host factors, such as ...

Ethiopia has the largest livestock inventories among African countries. Recent reports showed that, 56.71 million heads of cattle, 29.33 million sheep, 29.11 million goats and 54.5 million chickens are found in Ethiopia ( Agricultural Sample Survey 2015/16). Even though the country is endowed with this wealth, it happens to be the corridor of many internationally important livestock disease among others ...

Allogeneic hematopoietic stem cell transplantation (alloHCT) induces severe immunosuppression persisting several months after transplantation, particularly in patients suffering from chronic graft-versus-host disease. Asa consequence, they are at high risk of dying following infection with the SARS-CoV-2 or the influenzae virus. It is thus critical to protect them against these pathogens with efficient vaccination. This is not an easy task ...