Validation of UDPG:PP as an anti‐virulence drug target against Streptococcus pneumoniae infections using Galleria mellonella as an alternative in vivo model University of Antwerp
The pneumococcus Streptococcus pneumoniae is considered one of the most important human pathogens. Infection can lead to diseases such as meningitis, pneumonia and otitis media. Especially children, the elderly and immunocompromised patients are at risk for developing severe infections. While several vaccines exist, they do not cover the entire pneumococcal spectrum. Moreover, a switch towards non-vaccine serotypes has been observed. Also, ...