Publications
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Development of a controlled release formulation by continuous twin screw granulation : influence of process and formulation parameters Ghent University
Influence of binder attributes on binder effectiveness in a continuous twin screw wet granulation process via wet and dry binder addition Ghent University
Continuous twin screw granulation of controlled release formulations with various HPMC grades Ghent University
Stability and repeatability of a continuous twin screw granulation and drying system Ghent University
The effect of binder types on the breakage and drying behavior of granules in a semi-continuous fluid bed dryer after twin screw wet granulation Ghent University
Current study investigated the effect of different binder types on the granule drying process and the granule breakage behavior in a semi-continuous fluid bed dryer integrated in the C25 ConsiGma-system. The studied binders (i.e. hydroxypropyl pea starch, hydroxypropyl methylcellulose E15, polyvinylpyrrolidone K12, and starch octenyl succinate CO 01) required different liquid amounts to produce similar granule quality. These different liquid ...