The role of BRCA1 as oncogenic replicative stress resistor in MYCN driven neuroblastoma Ghent University
Sequencing of cancer genomes has generated a tremendous amount of new information that is
currently translated towards novel approaches for patient tailored (so called precision medicine)
treatment. In embryonal tumors such as neuroblastoma however, mutations are sparse thus
hampering such an approach. Interestingly, despite this relative lack of recurrent mutations,
specific patterns of chromosome copy number ...