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Researcher
Carlos Dotti
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing, Laboratory medicine
Affiliations
- Research Group Molecular Neurobiology (VIB-KU Leuven) (Division)
Member
From1 Jan 2019 → 31 Dec 2019 - Laboratory of Neuronal Differentiation (VIB-KU Leuven Center for Brain & Disease Research) (Lab)
Member
From1 Jan 2017 → 31 Dec 2018 - Department of Human Genetics (Department)
Member
From1 Apr 2009 → 31 Dec 2016
Projects
1 - 6 of 6
- Combating age-dependent deficits in synaptic plasticity and cognition by preventing cholesterol loss in the neuronal plasma membrane.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Microglia as a missing link in the embryological development of neuropsychiatric disorders.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project
- Mechanism of neuronal survival during aging: relationship to performance.From1 Oct 2011 → 31 Oct 2012Funding: BOF - Other initiatives
- Molecular determinants of axon-dendrite specification in relation to neuronal migration and mental retardation disorders.From1 Jan 2010 → 31 Dec 2015Funding: FWO research project
- Characterization of aging genes in Drosophila nervous systemFrom1 Oct 2009 → 1 Oct 2013Funding: Own budget, for example: patrimony, inscription fees, gifts
- Functional Peptidomics Knowledge Platform.From1 Oct 2009 → 30 Sep 2013Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 73
- Radial somatic F-actin organization affects growth cone dynamics during early neuronal development(2019)Published in: EMBO ReportsISSN: 1469-221XIssue: 12Volume: 20
- Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism(2019)Published in: Frontiers in neurologyISSN: 1664-2295Volume: 10
- Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization(2019)Published in: Aging CellISSN: 1474-9718Issue: 3Volume: 18
- Increased Insoluble Amyloid-beta Induces Negligible Cognitive Deficits in Old App(NL /NL) Knock-In Mice(2018)Published in: Journal of Alzheimer's DiseaseISSN: 1387-2877Issue: 2Volume: 66Pages: 801 - 809
- High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease(2018)Published in: Neurobiology of DiseaseISSN: 0969-9961Volume: 113Pages: 82 - 96
- Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?(2018)Published in: EMBO Molecular MedicineISSN: 1757-4676Issue: 1Volume: 10Pages: 7 - 9
- E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion(2017)Published in: OncotargetISSN: 1949-2553Issue: 52Volume: 8Pages: 89439 - 89450
- Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity (vo20l 12, e0171968, 2017)(2017)Published in: PLOS ONEISSN: 1932-6203Issue: 10Volume: 12
- Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity (Vol 12, e0171968, 2017)(2017)Published in: PLOS ONEISSN: 1932-6203Issue: 7Volume: 12
- Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival(2017)Published in: Molecular CellISSN: 1097-2765Issue: 3Volume: 66Pages: 358 - +