Organisation
Laboratory for Biochemical Neuroendocrinology
Division
The Laboratory for Biochemical Neuroendocrinology conducts research into protein biosynthesis, maturation and trafficking in the (regulated) secretory pathway, in relation to human diseases like diabetes, obesity and autism.
Current researchers
1 - 3 of 3 results
- John Creemers (Responsible)
- Ilaria Coppola (Member)
- Yenthe Monnens (Member)
Projects
1 - 10 of 11
- Unraveling the pathology of the novel congenital myasthenic syndrome-22 (CMS22) and investigation of molecular links with Prader-Willi syndrome.From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The role of the proprotein convertases in diabetes and obesityFrom1 Sep 2016 → 12 Jul 2022Funding: FWO fellowships
- Functional characterization of PREPL and the role in Prader-Willi syndromeFrom1 Jan 2015 → 13 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of the proprotein convertase furin in cancerFrom22 Sep 2014 → 3 Aug 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of PREPL in regulated secretion and neuromuscular transmission.From21 Aug 2011 → 14 Sep 2014Funding: FWO fellowships
- (ATHEROGAG) Macrophage proteoglycans in atherosclerosis.From1 Jul 2011 → 15 Jun 2015Funding: Marie Curie - People
- Characterization of the regulated secretory pathway in neurons of a mouse model for autism.From1 Oct 2010 → 21 Mar 2016Funding: Private funding of national origin - undefined, FWO fellowships
- The role of furin in beta cell proliferation.From1 Aug 2009 → 19 Nov 2015Funding: IWT personal funding - strategic basic research grants
- Hyperplasia of the islets of Langerhans in transgenic mice with targeted PLAG1 overexpression in the pancreas.From1 Jan 2009 → 31 Dec 2011Funding: FWO research grant KAN
- The role of PREPL in hypotonia-cystinuria syndromeFrom8 Sep 2008 → 31 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 82
- ApoE is an important mediator of LRP1 functions in the lipid metabolism, adipogenesis and glucose homeostasis(2009)
Authors: Philip Gordts, Alexander Bartelt, Joerg Heeren, Anton Roebroek
- The Autism Candidate Gene Neurobeachin Encodes a Scaffolding Protein Implicated in Membrane Trafficking and Signaling(2011)
Authors: Karolien Volders, Kim Nuytens, John Creemers
Pages: 204 - 217 - Effectiveness of implant-supported fixed partial denture in patients with history of periodontitis: A systematic review and meta-analysis(2021)
Authors: Krizia Tuand, Katleen Vandamme
Pages: 208 - 223 - Normal cognitive outcome in a PEX6 deficient girl despite neonatal multisystem presentation(2016)
Authors: Peter Witters, Luc Régal, Eva Morava
Pages: 1642 - 6 - Neuromyelitis optica-IgG(+) optic neuritis associated with celiac disease and dysgammaglobulinemia: A role for tacrolimus?(2011)
Authors: Isabelle Meyts, Katrien Jansen, Xavier Bossuyt, Luc Régal, Lieven Lagae, Gunnar Buyse
Pages: 265 - 267 - Het ontrafelen van de rol van PREPL, een serine hydrolase gedeleteerd in een Prader-Willi-achtig syndroom(2021)
Authors: Karen Rosier, John Creemers
- Haploinsufficiency of the autism candidate gene Neurobeachin induces autism-like behaviors and affects cellular and molecular processes of synaptic plasticity in mice(2013)
Authors: Kim Nuytens, Ilse Gantois, Pieter Stijnen, Emilia Iscru, Annelies Laeremans, Lien Van Eylen, Koenraad Devriendt, Detlef Balschun, Lut Arckens, John Creemers, et al.
Pages: 144 - 151 - Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic β Cells of Mice(2021)
Authors: Ilaria Coppola, John Creemers
- Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity(2016)
Authors: Pieter Stijnen, Bas Brouwers, Eva Dirkx, Frans Schuit, Lieven Thorrez, Jeroen Declercq, John Creemers
Pages: 973 - 981 - Novel Infantile-Onset Leukoencephalopathy With High Lactate Level and Slow Improvement(2012)
Authors: Luc Régal
Pages: 718 - 722