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Researcher
Lies Langouche
- Disciplines:Intensive care and emergency medicine not elsewhere classified
Affiliations
- Laboratory of Intensive Care Medicine (Division)
Member
From1 May 2004 → Today
Projects
1 - 10 of 24
- Toward individualized nutrition in critically ill patients: from unraveling and identifying metabolic dysregulation to therapeutic interventionsFrom1 Jan 2025 → TodayFunding: FWO research project (including WEAVE projects)
- On the role of lipid droplet-associated proteins and of pro-opiomelanocortin fragments in the pathophysiology of ICU-acquired muscle weakness and adrenal insufficiency in prolonged critical illnessFrom3 Oct 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring a novel, shared upstream pathway as potential driver of ICU-acquired muscle weakness and central adrenal insufficiency in prolonged critical illnessFrom1 Oct 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Metabolic reprogramming in critical illnessFrom16 Sep 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Circulating glucose and ketones as potential mediators of short- and long-term outcome of critical illnessFrom19 Jul 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A novel hybrid metabolomics platform combining the power of gas chromatography separation with highresolution, high-accuracy mass spectrometry of full precursor masses.From1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Impact of the nutritional status on metabolic dysregulation during critical illness. Can metabolic interventions restore mitochondrial homeostasis?From9 Sep 2021 → 17 Sep 2025Funding: Own budget, for example: patrimony, inscription fees, gifts
- Impact of duration of critical illness on cholesterol availability in relation to outcomeFrom1 Sep 2021 → 25 Sep 2025Funding: Own budget, for example: patrimony, inscription fees, gifts
- Improving monitoring of cardiac function in critical illness: from advanced echocardiographic technology to metabolic and biochemical biomarkers predicting myocardial dysfunction.From12 May 2021 → 12 May 2025Funding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of the role of mechanosensors in skeletal muscle mass homeostasis and maintenanceFrom14 Apr 2021 → 14 Apr 2025Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 115
- A pilot study on midazolam sedation for murine echocardiography: A potential alternative to isoflurane anesthesia and awake imaging(2025)Published in: Physiological ReportsISSN: 2051-817XIssue: 21Volume: 13
- Kennis kent geen einde. De beweging van de universiteit(2025)Number of pages: 152
- Impact of duration of critical illness on cholesterol availability in relation to outcome(2025)
- Impact of the nutritional status on metabolic dysregulation during critical illness. Can metabolic interventions restore mitochondrial homeostasis?(2025)
- Low-Dose Hydrocortisone in Cirrhotic Patients With Septic Shock: A Double-Blind Randomised Placebo-Controlled Trial(2025)Published in: Liver internationalISSN: 1478-3223Issue: 9Volume: 45
- Alterations in the lipid profile of critically ill children in relation to outcome(2025)Published in: Crit CareISSN: 1364-8535Issue: 1Volume: 29
- A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart(2025)Published in: Intensive Care Medicine ExperimentalISSN: 2197-425XIssue: 1Volume: 13
- Glucocorticoid treatment increases cholesterol availability during critical illness: effect on adrenal and muscle function(2024)Published in: Crit CareISSN: 1364-8535Issue: 1Volume: 28
- Pro-opiomelanocortin and ACTH-cortisol dissociation during pediatric cardiac surgery(2024)Published in: Endocr ConnectISSN: 2049-3614Issue: 6Volume: 13
- Our Scientific Journey through the Ups and Downs of Blood Glucose Control in the ICU(2024)Published in: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINEISSN: 1073-449XIssue: 5Volume: 209Pages: 497 - 506
Linked dataset
1 - 5 of 5
- Replication Data for: Alterations in the lipid profile of critically ill children in relation to outcome. Lauren De Bruyn et al. Crit Care 2025. doi.org/10.1186/s13054-025-05327-5
- Replication Data for: A murine model of acute and prolonged abdominal sepsis, supported by intensive care, reveals time-dependent metabolic alterations in the heart. Bart Jacobs et al. ICMx 2025.
- Replication Data for: Impact of rAAV-shRNA treatment targeting mechanosensitive Ilk1 and Fermt2 in a mouse model of sepsis-induced muscle weakness
- Replication Data for: A pilot study on midazolam sedation for murine echocardiography: A potential alternative to isoflurane anesthesia and awake imaging
- Replication Data for: Glucocorticoid treatment increases cholesterol availability during critical illness: effect on adrenal and muscle function. Lauren De Bruyn et al. Crit Care 2024.