Researcher
Sophie Steeland
- Disciplines:Biophysics, Molecular and cell biology, Laboratory medicine, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry
Affiliations
- Department of Biomedical molecular biology (Department)
Member
From3 Sep 2012 → 31 Dec 2018
Projects
1 - 2 of 2
- Deciphering the role of extracellular vesicles (EVs) in multiple sclerosis (MS)From1 Oct 2018 → 31 Dec 2022Funding: FWO fellowships
- The development of strong specific, efficient, flexible and safe TNF-receptor inhibitors for treatment of acute and chronic inflammatory diseases.From1 Oct 2013 → 23 Oct 2017Funding: BOF - Other initiatives, FWO fellowships
Publications
1 - 10 of 13
- Choroid plexus tumor necrosis factor receptor 1 : a new neuroinflammatory piece of the complex Alzheimer's disease puzzle(2019)
Authors: Sophie Steeland
Pages: 1144 - 1147 - A study of cecal ligation and puncture-induced sepsis in tissue-specific tumor necrosis factor receptor 1-deficient mice(2019)
Authors: Jolien Vandewalle, Sophie Steeland, Sara Van Ryckeghem, Melanie Eggermont, Elien Van Wonterghem, Roosmarijn Vandenbroucke, Claude Libert
- A new venue of TNF targeting(2018)
Authors: Sophie Steeland, Claude Libert
- Simultaneous inhibition of tumor necrosis factor receptor 1 and matrix metalloproteinase 8 completely protects against acute inflammation and sepsis(2018)
Authors: Sophie Steeland, Sara Van Ryckeghem, Jolien Vandewalle, Marlies Ballegeer, Elien Van Wonterghem, Melanie Eggermont, Johan Decruyenaere, Liesbet De Bus, Claude Libert, Roosmarijn Vandenbroucke
Pages: e67 - e75 - Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease(2018)
Authors: Sophie Steeland, Nina Gorlé, Charysse Vandendriessche, Sriram Balusu, Marjana Brkic, Caroline Van Cauwenberghe, Griet Van Imschoot, Elien Van Wonterghem, Anna Kremer, Saskia Lippens, et al.
- TNFR1 inhibition with a nanobody protects against EAE development in mice(2017)
Authors: Sophie Steeland, Sara Van Ryckeghem, Griet Van Imschoot, Wendy Toussaint, Leen Vanhoutte, Christian Vanhove, Filip De Vos, Claude Libert
- Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases(2017)
Authors: Sophie Steeland
- Efficient analysis of mouse genome sequences reveal many nonsense variants(2016)
Authors: Sophie Steeland, Steven Timmermans, Sara Van Ryckeghem, Yvan Saeys, Marc Van Montagu, Claude Libert
Pages: 5670 - 5675 - Nanobodies as therapeutics: big opportunities for small antibodies(2016)
Authors: Sophie Steeland, Claude Libert
Pages: 1076 - 1113 - Topical imiquimod yields systemic effects due to unintended oral uptake(2016)
Authors: Sophie Steeland, Sara Van Ryckeghem, Stefan Lienenklaus, Siegfried Weiss, Niek Sanders, Claude Libert
Patents
1 - 1 of 1
- Means and methods to treat inflammation (Inventor)