Organisation
Immunoparasitology (Rega Institute)
Lab
The aim of our malaria research program is to investigate the immunological and molecular mechanisms leading to complicated malaria and to design potential therapies.
Current researchers
1 - 7 of 7 results
- Philippe Van den Steen (Responsible)
- Alia Fazal Salom (Member)
- Emilie Pollenus (Member)
- Hendrik Possemiers (Member)
- Rebecca Sadler (Member)
- Philippe Van den Steen (Member)
- Leen Vandermosten (Member)
Projects
1 - 10 of 16
- CD8+ T cell mediated pathogenesis in malariaFrom7 Nov 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Leukocyte trafficking in the resolution of inflammationFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Mechanisms of disease resolution in severe malariaFrom19 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Immunopathogenesis of malaria-associated acute kidney injuryFrom12 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Reducing severe malaria related child mortality in the Democratic Republic of Congo (DRC) by improving the management and control of malaria associated kidney injury (MAKI)From1 Sep 2023 → TodayFunding: VLIR-UOS South Initiatives
- Disease resolution mechanisms and interrelation with dysmetabolism in severe malariaFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Inflammation and dysmetabolism in malariaFrom23 Sep 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Intravital microscopy platform for infectious and inflammatory diseasesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Glucocorticoid regulation of systemic immunometabolism in malariaFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- The interrelation between endogenous glucocorticoids, inflammation and metabolic disturbances in malariaFrom1 Oct 2019 → 18 Oct 2022Funding: FWO fellowships
Publications
1 - 10 of 83
- Virus entry inhibition by chlorite-oxidized oxyamylose versus induction of antiviral interferon by poly(I:C)(2008)
Authors: Sandra Li, Philippe Van den Steen, Ghislain Opdenakker
Pages: 831 - 840 - Interplay of hemozoin and host factors in malaria immunopathogenesis(2011)
Authors: Nathalie Geurts, Ghislain Opdenakker, Philippe Van den Steen
- Malaria: host-pathogen interactions, immunopathological, complications and therapy(2011)
Authors: Philippe Van den Steen, Katrien Deroost, Nathalie Geurts, Hubertine Heremans, Jo Van Damme, Ghislain Opdenakker
Pages: 123 - 151 - Matrix metalloproteinase-9/gelatinase B is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis(2008)
Authors: Philippe Van den Steen, Ghislain Opdenakker
Pages: 34 - 46 - De pathogene rol van hemozoïne en endotheelactivatie in malaria geassocieerde acute respiratory distress syndrome(2020)
Authors: Thao-Thy Pham, Philippe Van den Steen, Ghislain Opdenakker
- Deficiency of gelatinase B/MMP-9 aggravates lpr-induced lymphoproliferation and lupus-like systemic autoimmune disease
Authors: Bénédicte Cauwe, Xavier Sagaert, Nathalie Geurts, Sandra Li, Hubertine Heremans, Philippe Van den Steen, Rita De Vos, Daniel Engelbert Blockmans, Ghislain Opdenakker
Pages: 239 - 252 - A catalytically inactive gelatinase B/MMP-9 mutant impairs homing of chronic lymphocytic leukemia cells by altering migration regulatory pathways(2018)
Authors: Estefania Ugarte Berzal, Philippe Van den Steen, Ghislain Opdenakker
Pages: 124 - 130 - Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65(2018)
Authors: Philippe Van den Steen
Pages: 18 - Endothelial response to glucocorticoids in inflammatory diseases(2016)
Authors: Karolina Zielinska, Ghislain Opdenakker, Philippe Van den Steen
- Natural haemozoin induces expression and release of human monocyte tissue inhibitor of metalloproteinase-1(2013)
Authors: Ghislain Opdenakker, Philippe Van den Steen