From gene to aortic dissection - detailed study of the etiology and pathogenesis and of cardiovascular characteristics of inheritable thoracic aortic aneurysms and dissections

Aortic aneurysms are associated with significant morbidity and mortality. Study of genetic causes of aortic aneurysms allows us to gain better insights into the underlying pathogenesis and may offer new targets for optimizing treatment. With this project, we aim to search for new genes and gain better insights into the moecualr pathways of aneurysm formation.