A new Colorimetric Test for Solid-phase Amines and thiols

Abstract:A new, efficient, sensitive, and reliable color test for the visual detection of resin-bound primary and secondary amines is described. The reaction between amines and 1-methyl-2-(4'-nitrophenyl)-imidazo[1,2- a]pyrimidinium perchlorate (DESC) provides the "on-bead generated" colored stable intermediate azadiene. The developed protocols allow detection of resin-bound primary amines in the presence of secondary amines. The test can also be used for the detection of resin bound thiols.

Publication year:2008

Keywords:Multidisciplinary chemistry, Applied chemistry & chemical engineering, Organic & medicinal chemistry

BOF-keylabel:yes

IOF-keylabel:yes

BOF-publication weight:3

CSS-citation score:1

Authors from:Higher Education

Review status:Peer-reviewed