Researcher
Aernout Luttun
- Disciplines:Vascular diseases, Cardiac and vascular medicine not elsewhere classified, Stem cell biology, Cell therapy
Affiliations
- Centre for Molecular and Vascular Biology (Division)
Member
From1 Jan 2002 → Today
Projects
1 - 10 of 31
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Study of the cellular and molecular mechanisms underlying cardiomyopathy caused by transcription factor PR domain containing 16 (Prdm16) deficiency in cardiomyocytes and non-cardiomyocyte cell typesFrom1 Apr 2022 → TodayFunding: Other federal public and semi-governmental institutions
- Unraveling the role of transcription factor Prdm16 in regulating the cellular and (epi)genetic landscape of atherosclerosis at single-cell resolutionFrom21 Aug 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unravelling the cellular landscape and the up- and downstream molecular mechanisms of peripheral arterial disease at single-cell resolutionFrom1 Jan 2021 → TodayFunding: FWO research project
- BMP signaling in vascular biology and disease.From1 Jan 2020 → TodayFunding: FWO scientific research network
- Genes and mechanics: how tissue-specific endothelial cell heterogeneity arisesFrom1 Oct 2019 → TodayFunding: BOF - projects
- BMP signalling in endothelial function and dysfunctionFrom1 Oct 2019 → TodayFunding: BOF - projects
- Reduced BMP-SMAD signalling levels in the maternal vasculature, a potential risk for pre-eclampsiaFrom1 Oct 2018 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mass cytometry by time-of-flight: next-generation flow cytometry for multiplexed single cell analysisFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Development and validation of a repurposing platform for drug discovery to treat cardiomyopathy.From1 Oct 2016 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 74
- Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model.(2022)
Authors: Tom Van Loy, Steven De Jonghe, Wouter Dheedene, Patrick Chaltin, Aernout Luttun, Dominique Schols
Pages: 293 - Organ-Specific Endothelial Cell Differentiation and Impact of Microenvironmental Cues on Endothelial Heterogeneity(2022)
Authors: Laia Gifre Renom, Margo Daems, Aernout Luttun, Elizabeth Jones
Number of pages: 29 - Association of colorectal cancer with genetic and epigenetic variation in PEAR1-A population-based cohort study.(2022)
Authors: Marc Hoylaerts, Aernout Luttun, Peter Verhamme, Zhenyu Zhang
Pages: e0266481 - Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function(2021)
Authors: Sander Craps, Jore Van Wauwe, Tim Vervliet, Wouter Dheedene, Nathan Criem, Elizabeth Jones, An Clementine Zwijsen, Diether Lambrechts, Aernout Luttun
Pages: 63 - 77Number of pages: 15 - The BMP Pathway in Blood Vessel and Lymphatic Vessel Biology(2021)
Authors: Ljuba Ponomarev, Jakub Ksiazkiewicz, Aernout Luttun, An Clementine Zwijsen
Number of pages: 31 - Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis(2021)
Authors: Willemke de Haan, Wouter Dheedene, Baki Topal, An Clementine Zwijsen, Danny Huylebroeck, Aernout Luttun
Pages: 1262 - 1275Number of pages: 14 - Microvascular Endothelium in Heart Failure(2021)
Authors: Sander Trenson, Stefan Janssens, Aernout Luttun
- Cardiac Microvascular Endothelial Cells in Pressure Overload-Induced Heart Disease(2021)
Authors: Sander Trenson, Sander Craps, Peter Pokreisz, Jore Van Wauwe, Denise Veltman, Rik Gijsbers, Jan Staessen, Bart Ghesquière, Peter Carmeliet, Filip Rega, et al.
Pages: 97 - 111Number of pages: 15 - Multipotent adult progenitor cells grown under xenobiotic-free conditions support vascularization during wound healing(2020)
Authors: Aernout Luttun
Number of pages: 14 - Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization(2020)
Authors: Willemke de Haan, Wouter Dheedene, Baki Topal, Catherine Verfaillie, Aernout Luttun
Pages: G803 - G815Number of pages: 13