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Researcher
Inge Depoortere
- Disciplines:Endocrinology and metabolic diseases, Gastro-enterology and hepatology, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 1999 → Today
Projects
11 - 20 of 21
- Neuro-hormonal control of hunger, nutrient tolerance and food intake : from nutrient sensing to reward sensitivity.From1 Jan 2016 → 31 Dec 2022Funding: BOF - Methusalem
- Activation of endocrine and innate immune responses by tastants in the human gut epithelium: impact of obesityFrom12 Oct 2015 → 7 Oct 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Interplay between short-chain fatty acids and the circadian clock in the rhythmicity of contractility and hormone release in the gutFrom1 Oct 2015 → 4 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Bitter chemosensory pathways in the gut regulate reward sensitivity and food intakeFrom1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Development of novel selective ghrelin O-acyltransferase inhibitors for the treatment of obesity and obesity-related type 2 diabetesFrom1 Apr 2014 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Making sense of what we eat: amino acid taste receptors tune ghrelin release and smooth muscle contractilityFrom1 Sep 2012 → 18 Jun 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Sensing of prebiotic carbohyddrates in the gut via taste receptors: role in the control of food intake.From1 Sep 2012 → 1 Mar 2017Funding: IWT personal funding - strategic basic research grants
- Role of peripheral clock genes in the circadian regulation of the hunger hormone ghrelin.From1 Oct 2010 → 9 Oct 2015Funding: FWO fellowships
- Role of taste receptors and the G-protein, alpha-gustducin, in the regulation of ghrelin secretion.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
- Gastro-intestinal regulation mechanisms.From1 Jan 2009 → 31 Dec 2020Funding: FWO scientific research network
Publications
1 - 10 of 154
- SCFAs switch stem cell fate through HDAC inhibition to improve barrier integrity in 3D intestinal organoids from patients with obesity(2023)
Authors: Mona Farhadipour, Kaline Arnauts, Mathias Clarysse, Bart Van Der Schueren, Laurens Ceulemans, Ellen Deleus, Matthias Lannoo, Marc Ferrante, Inge Depoortere
- The Acute Effect of Hydroxychloroquine Sulfate on Hunger, the Plasma Concentration of Orexigenic Peptides and Hedonic Food Intake: A Pilot Study(2023)
Authors: Christophe Matthys, Inge Depoortere, Jan Tack
- Controlled light exposure and intermittent fasting as treatment strategies for metabolic syndrome and gut microbiome dysregulation in night shift workers(2023)
Authors: Inge Depoortere
- Chronic jetlag reprograms gene expression in the colonic smooth muscle layer inducing diurnal rhythmicity in the effect of bile acids on colonic contractility(2023)
Authors: Inge Depoortere
- ROLE OF BITTER TASTE RECEPTORS IN THE HUMAN INTESTINE IN THE REGULATION OF METABOLISM AND INNATE IMMUNITY DURING OBESITY.(2023)
Authors: Inge Depoortere
- Tuning feeding time to prevent the effects of chronodisruption in the gut induced by chronic jetlag(2022)
Authors: Louis Desmet, Inge Depoortere
- Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity(2022)
Authors: Kathrin Liszt, Mona Farhadipour, Ellen Deleus, Bart Van Der Schueren, Laurens Ceulemans, Matthias Lannoo, Jan Tack, Inge Depoortere
- Reply to Erren et al. Chronodisruption: Origin, Roots, and Developments of an 18-Year-Old Concept. Comment on "Desmet et al. Time-Restricted Feeding in Mice Prevents the Disruption of the Peripheral Circadian Clocks and Its Metabolic Impact during Chronic Jetlag. Nutrients 2021, 13, 3846"(2022)
Authors: Louis Desmet, Kristin Verbeke, Inge Depoortere
- Chronodisruption by chronic jetlag impacts metabolic and gastrointestinal homeostasis in male mice(2021)
Authors: Louis Desmet, Kristin Verbeke, Inge Depoortere
- Time-Restricted Feeding in Mice Prevents the Disruption of the Peripheral Circadian Clocks and Its Metabolic Impact during Chronic Jetlag(2021)
Authors: Louis Desmet, Kristin Verbeke, Inge Depoortere