Researcher
Niels HELLINGS
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Autoimmunity
Affiliations
- Immunology & Infection (Department)
Member
From1 Jan 2020 → Today - Immunology & Infection (Research group)
Member
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Responsible
From1 May 2016 → Today - Biomedical Research Institute (Research institute)
Member
From1 Nov 2000 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Nov 2000 → Today - Physiology - Biochemistry - Immunology (Department)
Member
From1 Oct 2003 → 31 Dec 2019 - Immunology - Biochemistry (Research group)
Member
From1 Nov 2000 → 31 Dec 2019 - Medical Basic Sciences (Division)
Member
From1 Nov 2000 → 30 Sep 2009
Projects
31 - 40 of 87
- Restoring defective regulators: a step towards an autologous regulatory T cell-based therapy for multiple sclerosisFrom1 Jan 2020 → 31 Mar 2022Funding: FWO Strategic Basic Research Grant
- Identification of key molecules involved in the recruitment of pathogenic T cells into the inflamed MS brainFrom1 Oct 2019 → 30 Sep 2023Funding: BOF - doctoral mandates
- High performance decision support systems for multiple sclerosis treatment effectiveness in a real-world settingFrom1 Oct 2019 → 30 Sep 2022Funding: FWO senior postdoctoral fellowship
- IOF mandate Biomedical Research Institute 2019-2023From1 Jul 2019 → 31 Dec 2023Funding: IOF - mandates
- Towards personalized medicine: predicting disease progression of MS patients from trajectory dataFrom15 Jun 2019 → 31 Aug 2019Funding: BOF - mobility
- PDE4D inhibition & pMS: IP valuation and valorization roadmapsFrom1 Apr 2019 → 31 Mar 2020Funding: IOF - technology validation in lab
- Targeting enzymes on the splice variants level, a novel approach to boost repair in multiple sclerosisFrom1 Feb 2019 → 31 Jan 2021Funding: FWO Strategic Basic Research Grant
- Relieving the epigenetic blockade in progressive multiple sclerosis – making repair possible againFrom17 Jan 2019 → 31 Dec 2019Funding: Nonprofit institution or equivalents
- The epigenetic signature of myelin genes as innovative biomarker for progressive multiple sclerosisFrom1 Jan 2019 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Unraveling the hidden pathways of inhaled combustion-derived particles from air pollutionFrom1 Oct 2018 → 9 Nov 2020Funding: FWO fellowships
Publications
1 - 10 of 179
- The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis(2024)
Authors: Assia TIANE, Veerle SOMERS, Niels HELLINGS, DLA van den Hove, Tim VANMIERLO
- The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation(2024)
Authors: Emily WILLEMS, Melissa SCHEPERS, Elisabeth PICCART, Esther WOLFS, Niels HELLINGS, Maria Ait-Tihyaty, Tim VANMIERLO
- Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs(2024)
Authors: Paulien BAETEN, Ibrahim HAMAD, Cindy HOEKS, Michael Hiltensperger, Bart VAN WIJMEERSCH, Veronica POPESCU, Lilian Aly, Veerle SOMERS, Thomas Korn, Markus KLEINEWIETFELD, et al.
- Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury(2023)
Authors: Femke Mussen, Jana VAN BROECKHOVEN, Niels HELLINGS, Melissa SCHEPERS, Tim VANMIERLO
- From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions(2023)
Authors: Assia TIANE, Melissa SCHEPERS, Rick A. Reijnders, Lieve VAN VEGGEL, Sarah CHENINE, Ben ROMBAUT, Emma Dempster, Catherine Verfaillie, Kobi Wasner, Anne Gruenewald, et al.
Pages: 283 - 299 - Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity(2023)
Authors: Elien GRAJCHEN, Melanie LOIX, Paulien BAETEN, Beatriz FERNANDES CORTE-REAL, Ibrahim HAMAD, Sam VANHERLE, Mansour HAIDAR, Jonas Dehairs, Jelle Y. Broos, James M. Ntambi, et al.
Pages: 666 - 679 - Train your T cells: How skeletal muscles and T cells keep each other fit during aging(2023)
Authors: Leen SLAETS, Lena FONTEYN, Bert OP 'T EIJNDE, Niels HELLINGS
Pages: 237 - 244 - Differential Runx3, Eomes, and T-bet expression subdivides cytotoxic CD4+memory T cells with brain-homing capacity(2023)
Authors: Cindy HOEKS, Fabienne van Puijfelik, Steven Koetzier, Jasper Rip, Cato Corsten, Annet Wierenga-Wolf, Marie-Jose Melief, Piet STINISSEN, Joost Smolders, Niels HELLINGS, et al.
Pages: 232 - Comprehensive antibody and cytokine profiling in hospitalized COVID-19 patients in relation to clinical outcomes in a large Belgian cohort(2023)
Authors: Pieter RUYTINX, Patrick VANDORMAEL, Judith FRAUSSEN, Zoe PIETERS, Stef Thonissen, Niels HELLINGS, Piet STINISSEN, Ina CALLEBAUT, Joris PENDERS, Karolien VANHOVE, et al.
- Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs(2023)
Authors: Beatriz FERNANDES CORTE-REAL, Ibrahim HAMAD, Rebeca ARROYO HORNERO, Sabrina Geisberger, Joris Roels, Lauren VAN ZEEBROECK, Aleksandra DYCZKO, Marike W. van Gisbergen, Henry Kurniawan, Allon Wagner, et al.
Pages: 299 - 315