Researcher
Niels HELLINGS
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Autoimmunity
Affiliations
- Immunology & Infection (Department)
Member
From1 Jan 2020 → Today - Immunology & Infection (Research group)
Member
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Responsible
From1 May 2016 → Today - Biomedical Research Institute (Research institute)
Member
From1 Nov 2000 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Nov 2000 → Today - Physiology - Biochemistry - Immunology (Department)
Member
From1 Oct 2003 → 31 Dec 2019 - Immunology - Biochemistry (Research group)
Member
From1 Nov 2000 → 31 Dec 2019 - Medical Basic Sciences (Division)
Member
From1 Nov 2000 → 30 Sep 2009
Projects
71 - 80 of 87
- FWO research project: A role for expanded CD4+CD28null T cells in patients with multiple sclerosis?From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- A pathogenic role for cytotoxic CD4+CD28null T-cells in multiple sclerosis?From1 Jan 2012 → 31 Dec 2013Funding: Foundations, funds and other with scientific goal
- Oncostatin M as a master regulator of central nervous system lesion pathologyFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- The multiple faces of microglia in brain diseases. Phenotyping microglia in the acute-chronic switch of autoimmune, traumatic and excitability disordersFrom1 Jan 2011 → 31 Dec 2015Funding: BOF - Concerted Research Project from 1994
- Therapeutic application of multipotent stem cells in an animal model of multiple sclerosisFrom1 Jan 2010 → 31 Dec 2013Funding: IWT personal funding - strategic basic research grants
- Multiple Sclerosis, a multidisciplinary appraochFrom1 Jan 2010 → 31 Dec 2014Funding: FWO scientific research network
- Protective effects of neuropoietic cytokines on pathological CNS responses in multiple sclerosisFrom1 Jan 2010 → 31 Dec 2013Funding: BOF - Doctoral projects
- Can non-invasive brain stimulation enhance neuroplasticity mediated by brain-derived neurotrophic factor (BDNF) in the healthy and injured brain: a new therapeutic tool for improving recovery after stroke?From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Validation of advanced, macrophage-targeted vaccines for MSFrom1 Jan 2010 → 31 Dec 2012Funding: IOF - Industrial Research Fund
- Dendritic cells as mediators of regulatory T-cell processes in multiple sclerosisFrom1 Jan 2010 → 31 Dec 2013Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 179
- The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis(2024)
Authors: Assia TIANE, Veerle SOMERS, Niels HELLINGS, DLA van den Hove, Tim VANMIERLO
- The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation(2024)
Authors: Emily WILLEMS, Melissa SCHEPERS, Elisabeth PICCART, Esther WOLFS, Niels HELLINGS, Maria Ait-Tihyaty, Tim VANMIERLO
- Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs(2024)
Authors: Paulien BAETEN, Ibrahim HAMAD, Cindy HOEKS, Michael Hiltensperger, Bart VAN WIJMEERSCH, Veronica POPESCU, Lilian Aly, Veerle SOMERS, Thomas Korn, Markus KLEINEWIETFELD, et al.
- Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury(2023)
Authors: Femke Mussen, Jana VAN BROECKHOVEN, Niels HELLINGS, Melissa SCHEPERS, Tim VANMIERLO
- From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions(2023)
Authors: Assia TIANE, Melissa SCHEPERS, Rick A. Reijnders, Lieve VAN VEGGEL, Sarah CHENINE, Ben ROMBAUT, Emma Dempster, Catherine Verfaillie, Kobi Wasner, Anne Gruenewald, et al.
Pages: 283 - 299 - Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity(2023)
Authors: Elien GRAJCHEN, Melanie LOIX, Paulien BAETEN, Beatriz FERNANDES CORTE-REAL, Ibrahim HAMAD, Sam VANHERLE, Mansour HAIDAR, Jonas Dehairs, Jelle Y. Broos, James M. Ntambi, et al.
Pages: 666 - 679 - Train your T cells: How skeletal muscles and T cells keep each other fit during aging(2023)
Authors: Leen SLAETS, Lena FONTEYN, Bert OP 'T EIJNDE, Niels HELLINGS
Pages: 237 - 244 - Differential Runx3, Eomes, and T-bet expression subdivides cytotoxic CD4+memory T cells with brain-homing capacity(2023)
Authors: Cindy HOEKS, Fabienne van Puijfelik, Steven Koetzier, Jasper Rip, Cato Corsten, Annet Wierenga-Wolf, Marie-Jose Melief, Piet STINISSEN, Joost Smolders, Niels HELLINGS, et al.
Pages: 232 - Comprehensive antibody and cytokine profiling in hospitalized COVID-19 patients in relation to clinical outcomes in a large Belgian cohort(2023)
Authors: Pieter RUYTINX, Patrick VANDORMAEL, Judith FRAUSSEN, Zoe PIETERS, Stef Thonissen, Niels HELLINGS, Piet STINISSEN, Ina CALLEBAUT, Joris PENDERS, Karolien VANHOVE, et al.
- Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs(2023)
Authors: Beatriz FERNANDES CORTE-REAL, Ibrahim HAMAD, Rebeca ARROYO HORNERO, Sabrina Geisberger, Joris Roels, Lauren VAN ZEEBROECK, Aleksandra DYCZKO, Marike W. van Gisbergen, Henry Kurniawan, Allon Wagner, et al.
Pages: 299 - 315