Basic (bio-) Medical Sciences Vrije Universiteit Brussel
Basic and applied biomedical research, and biomedical science-based higher education.
Basic and applied biomedical research, and biomedical science-based higher education.
The Department of Cell Biology (CYTO-VUB) is specialized in molecular and cellular liver research, with a main focus on the (patho)biology of hepatic stellate cells and liver progenitor cells. Prof. A. Geerts contributed to the first paper on isolation, purification and culturing of hepatic stellate cells (1) and is the author of a side scatter activated cell sorting method to purify freshly isolated hepatic stellate cell up to 95 - 100% (2). ...
The laboratory for Cell Genetics (Cytogenetics) studies variation in genotype and phenotype, cell division pathways, cell death and genetic changes relevant for the increase of cancer in human. Genotoxicity tests assess the induction of DNA damage, gene mutations, structural and numerical chromosome aberrations. Their predictivity for cancer induction is supported by international studies relating mutations and activation of cancer related ...
The research unit CIMM, founded by Patrick De Baetselier in 1983, initially focused on cellular immunology, mainly in the context of tumour biology. The basic themes were the analysis of immune escape mechanisms as well as the mechanisms involved in the invasive and metastatic behaviour of cancer cells. Since several common points may exist in the ways either cancer cells or parasites evade immune surveillance, cellular interactions involved ...
Topic A : Identification of new mutations in hereditary diseases (W. Lissens, I. Liebaers), more in particular: - cystic fibrosis - iduronate sulphate deficiency - Beta-glucuronidase deficiency - anti thrombosis III deficiency Topic B : Preimplantation genetics/expression (Liebaers I, Lissens W.) - expression Beta-hexosaminidase in mouse and human embryo's - preimplantation diagnosis in couples at risk for cysticfibrosis (F508) or couples at ...
General topic : The research aims a better understanding of the interaction of chemical agents with ionising radiation and/or hyperthermia Radiosensibilisation by microtubule inhibitors (Storme) Modulation of accumulation of Vinblastine and other Vincaalkaloids in MO4 cells by means of calcium entry blockers (Storme) Modulation of Cisplatin and Carboplatin toxicity and anti-tumor activity by vasco-active drugs in vivo (W. De Neve)
The EXPA research group brings together the clinical-pathological expertise of Prof. Ramses Forsyth and the more fundamental histopathologically oriented expertise of Prof. Peter in't Veld, thereby restoring the traditional interaction between a clinical UZ department and the Faculty in this (translational) biomedical research important domain. It will serve not only as a core facility for histopathology, but also as a platform for developing ...
The department AOSC mainly develops research in the areas of: 1. Organometallic Chemistry: Synthesis and characterisation of organotin compounds with potential anti-cancer activity. Structure determination (M. Gielen); 2. High Resolution Nuclear Magnetic Resonance Synthesis and characterisation of organotin polymers for applications in anion recognition and catalysis through advanced structure elucidation by multinuclear and multidimensional ...
HEIM is part of the Oncology Research Center and consists of a fundamental research team located at the Faculty of the Brussels Health Campus and a translational research team located at the University Hospital. Fundamental Research consists of cancer research in different tumor models including Multiple Myeloma, Acute Myeloid Leukemia and B-cell lymphoma. The aim of this research is to find novel therapeutic targets within the field of ...